IF1A_META3
ID IF1A_META3 Reviewed; 105 AA.
AC A6UUK8;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Translation initiation factor 1A {ECO:0000255|HAMAP-Rule:MF_00216};
DE Short=aIF-1A {ECO:0000255|HAMAP-Rule:MF_00216};
GN Name=eIF1A; OrderedLocusNames=Maeo_0595;
OS Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 /
OS Nankai-3).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=419665;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A.,
RA Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT "Complete sequence of Methanococcus aeolicus Nankai-3.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Seems to be required for maximal rate of protein
CC biosynthesis. Enhances ribosome dissociation into subunits and
CC stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal
CC subunits. {ECO:0000255|HAMAP-Rule:MF_00216}.
CC -!- SIMILARITY: Belongs to the eIF-1A family. {ECO:0000255|HAMAP-
CC Rule:MF_00216}.
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DR EMBL; CP000743; ABR56180.1; -; Genomic_DNA.
DR AlphaFoldDB; A6UUK8; -.
DR SMR; A6UUK8; -.
DR STRING; 419665.Maeo_0595; -.
DR EnsemblBacteria; ABR56180; ABR56180; Maeo_0595.
DR KEGG; mae:Maeo_0595; -.
DR eggNOG; arCOG01179; Archaea.
DR HOGENOM; CLU_109098_1_2_2; -.
DR OMA; ADITWRY; -.
DR Proteomes; UP000001106; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd05793; S1_IF1A; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR HAMAP; MF_00216; aIF_1A; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR InterPro; IPR001253; TIF_eIF-1A.
DR InterPro; IPR018104; TIF_eIF-1A_CS.
DR PANTHER; PTHR21668; PTHR21668; 1.
DR Pfam; PF01176; eIF-1a; 1.
DR SMART; SM00652; eIF1a; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR TIGRFAMs; TIGR00523; eIF-1A; 1.
DR PROSITE; PS01262; IF1A; 1.
DR PROSITE; PS50832; S1_IF1_TYPE; 1.
PE 3: Inferred from homology;
KW Initiation factor; Protein biosynthesis; Reference proteome.
FT CHAIN 1..105
FT /note="Translation initiation factor 1A"
FT /id="PRO_1000043279"
FT DOMAIN 12..87
FT /note="S1-like"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00216"
SQ SEQUENCE 105 AA; 12336 MW; A9FA50A26BC77D59 CRC64;
MQKKPMAPQQ PTRVRTPREE NNEILGIIEQ MLGASRVRVR CMDGHTRMGR IPGKLKRKIW
VREGDIVIVV PWEVQSDQKC DIIWRYTKGQ VSWLSKKGYL KQAYD