ID   IF1A_WHEAT              Reviewed;         144 AA.
AC   P47815;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Eukaryotic translation initiation factor 1A;
DE            Short=eIF-1A;
DE   AltName: Full=Eukaryotic translation initiation factor 4C;
DE            Short=eIF-4C;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   PARTIAL PROTEIN SEQUENCE, AND NUCLEOTIDE SEQUENCE OF 25-144.
RX   PubMed=8106356; DOI=10.1016/s0021-9258(17)41850-3;
RA   Dever T.E., Wei C.-L., Benkowski L.A., Browning K., Merrick W.C.,
RA   Hershey J.W.B.;
RT   "Determination of the amino acid sequence of rabbit, human, and wheat germ
RT   protein synthesis factor eIF-4C by cloning and chemical sequencing.";
RL   J. Biol. Chem. 269:3212-3218(1994).
CC   -!- FUNCTION: Seems to be required for maximal rate of protein
CC       biosynthesis. Enhances ribosome dissociation into subunits and
CC       stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal
CC       subunits.
CC   -!- SIMILARITY: Belongs to the eIF-1A family. {ECO:0000305}.
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DR   EMBL; L08060; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P47815; -.
DR   SMR; P47815; -.
DR   STRING; 4565.Traes_7DL_FCD23BB40.2; -.
DR   PRIDE; P47815; -.
DR   eggNOG; KOG3403; Eukaryota.
DR   Proteomes; UP000019116; Unplaced.
DR   ExpressionAtlas; P47815; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR   CDD; cd05793; S1_IF1A; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00216; aIF_1A; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR001253; TIF_eIF-1A.
DR   InterPro; IPR018104; TIF_eIF-1A_CS.
DR   PANTHER; PTHR21668; PTHR21668; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00652; eIF1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00523; eIF-1A; 1.
DR   PROSITE; PS01262; IF1A; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Initiation factor; Protein biosynthesis;
KW   Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT   CHAIN           2..144
FT                   /note="Eukaryotic translation initiation factor 1A"
FT                   /id="PRO_0000145111"
FT   DOMAIN          22..96
FT                   /note="S1-like"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..137
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         70
FT                   /note="W -> L (could be a sequencing error)"
FT   VARIANT         113
FT                   /note="V -> L (could be a sequencing error)"
SQ   SEQUENCE   144 AA;  16289 MW;  7BB10FD2756E4C9F CRC64;
     MPKNKGKGGK NRKRGKNEAD DDKRELVFKE DGQEYAQVTR MLGNGRCEAI CVDGTKRLCH
     IRGKMHKKVW IAAGDIVLVG LRDYQDDKAD VILKYMNDEA RLLKAYGELP DTVRLNEGVD
     VDGPEEGEGD SDYIQFEDED IDKI