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IF20B_XENLA
ID   IF20B_XENLA             Reviewed;         132 AA.
AC   Q640Z7;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Intraflagellar transport protein 20 homolog B;
GN   Name=ift20-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in ciliary process assembly. May play a role in the
CC       trafficking of ciliary membrane proteins from the Golgi complex to the
CC       cilium. Regulates the platelet-derived growth factor receptor-alpha
CC       (PDGFRA) signaling pathway. Plays an important role in spermatogenesis,
CC       particularly spermiogenesis, when germ cells form flagella.
CC       {ECO:0000250|UniProtKB:Q61025}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network
CC       {ECO:0000250|UniProtKB:Q61025}. Cytoplasm, cytoskeleton, microtubule
CC       organizing center, centrosome, centriole
CC       {ECO:0000250|UniProtKB:Q61025}. Cell projection, cilium
CC       {ECO:0000250|UniProtKB:Q61025}. Golgi apparatus
CC       {ECO:0000250|UniProtKB:Q61025}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q61025}.
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DR   EMBL; BC082442; AAH82442.1; -; mRNA.
DR   RefSeq; NP_001087895.1; NM_001094426.1.
DR   RefSeq; XP_018103858.1; XM_018248369.1.
DR   AlphaFoldDB; Q640Z7; -.
DR   SMR; Q640Z7; -.
DR   DNASU; 447756; -.
DR   GeneID; 447756; -.
DR   KEGG; xla:447756; -.
DR   CTD; 447756; -.
DR   Xenbase; XB-GENE-6253390; ift20.S.
DR   OMA; RARATXI; -.
DR   OrthoDB; 1589590at2759; -.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 447756; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:2000583; P:regulation of platelet-derived growth factor receptor-alpha signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   InterPro; IPR028172; FT20.
DR   PANTHER; PTHR31978; PTHR31978; 1.
DR   Pfam; PF14931; IFT20; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium biogenesis/degradation; Coiled coil; Cytoplasm;
KW   Cytoskeleton; Differentiation; Golgi apparatus; Reference proteome;
KW   Spermatogenesis.
FT   CHAIN           1..132
FT                   /note="Intraflagellar transport protein 20 homolog B"
FT                   /id="PRO_0000249307"
FT   COILED          87..112
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   132 AA;  15366 MW;  B5069338DFF8316D CRC64;
     MARDSLSEAG LHFDELNKLR ILDPDVSQQT TELKEECRDF VDKIGHFQKV VGGLIELVDE
     LAKETENEKM KAIGARNLLK SIAKQREAQQ QQLYALIAEK KMQLERYRIE YDALCKVEAE
     QHEFIDQFNL QK
 
 
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