IF20B_XENLA
ID IF20B_XENLA Reviewed; 132 AA.
AC Q640Z7;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Intraflagellar transport protein 20 homolog B;
GN Name=ift20-b;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Oocyte;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in ciliary process assembly. May play a role in the
CC trafficking of ciliary membrane proteins from the Golgi complex to the
CC cilium. Regulates the platelet-derived growth factor receptor-alpha
CC (PDGFRA) signaling pathway. Plays an important role in spermatogenesis,
CC particularly spermiogenesis, when germ cells form flagella.
CC {ECO:0000250|UniProtKB:Q61025}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network
CC {ECO:0000250|UniProtKB:Q61025}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriole
CC {ECO:0000250|UniProtKB:Q61025}. Cell projection, cilium
CC {ECO:0000250|UniProtKB:Q61025}. Golgi apparatus
CC {ECO:0000250|UniProtKB:Q61025}. Cytoplasm
CC {ECO:0000250|UniProtKB:Q61025}.
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DR EMBL; BC082442; AAH82442.1; -; mRNA.
DR RefSeq; NP_001087895.1; NM_001094426.1.
DR RefSeq; XP_018103858.1; XM_018248369.1.
DR AlphaFoldDB; Q640Z7; -.
DR SMR; Q640Z7; -.
DR DNASU; 447756; -.
DR GeneID; 447756; -.
DR KEGG; xla:447756; -.
DR CTD; 447756; -.
DR Xenbase; XB-GENE-6253390; ift20.S.
DR OMA; RARATXI; -.
DR OrthoDB; 1589590at2759; -.
DR Proteomes; UP000186698; Chromosome 2S.
DR Bgee; 447756; Expressed in egg cell and 19 other tissues.
DR GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR GO; GO:2000583; P:regulation of platelet-derived growth factor receptor-alpha signaling pathway; ISS:UniProtKB.
DR GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR InterPro; IPR028172; FT20.
DR PANTHER; PTHR31978; PTHR31978; 1.
DR Pfam; PF14931; IFT20; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cilium biogenesis/degradation; Coiled coil; Cytoplasm;
KW Cytoskeleton; Differentiation; Golgi apparatus; Reference proteome;
KW Spermatogenesis.
FT CHAIN 1..132
FT /note="Intraflagellar transport protein 20 homolog B"
FT /id="PRO_0000249307"
FT COILED 87..112
FT /evidence="ECO:0000255"
SQ SEQUENCE 132 AA; 15366 MW; B5069338DFF8316D CRC64;
MARDSLSEAG LHFDELNKLR ILDPDVSQQT TELKEECRDF VDKIGHFQKV VGGLIELVDE
LAKETENEKM KAIGARNLLK SIAKQREAQQ QQLYALIAEK KMQLERYRIE YDALCKVEAE
QHEFIDQFNL QK