ID   IF2B_METJA              Reviewed;         143 AA.
AC   Q57562;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=Translation initiation factor 2 subunit beta;
DE   AltName: Full=aIF2-beta;
DE   AltName: Full=eIF-2-beta;
GN   Name=eif2b; OrderedLocusNames=MJ0097;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98077.1; -; Genomic_DNA.
DR   PIR; A64312; A64312.
DR   RefSeq; WP_010869589.1; NC_000909.1.
DR   PDB; 1K81; NMR; -; A=108-143.
DR   PDB; 1K8B; NMR; -; A=39-90.
DR   PDBsum; 1K81; -.
DR   PDBsum; 1K8B; -.
DR   AlphaFoldDB; Q57562; -.
DR   BMRB; Q57562; -.
DR   SMR; Q57562; -.
DR   STRING; 243232.MJ_0097; -.
DR   EnsemblBacteria; AAB98077; AAB98077; MJ_0097.
DR   GeneID; 1450936; -.
DR   KEGG; mja:MJ_0097; -.
DR   eggNOG; arCOG01640; Archaea.
DR   HOGENOM; CLU_026663_3_1_2; -.
DR   InParanoid; Q57562; -.
DR   OMA; GKPDTRL; -.
DR   OrthoDB; 96453at2157; -.
DR   PhylomeDB; Q57562; -.
DR   EvolutionaryTrace; Q57562; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IBA:GO_Central.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; PTHR23001; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   TIGRFAMs; TIGR00311; aIF-2beta; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..143
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_0000137421"
FT   STRAND          40..43
FT                   /evidence="ECO:0007829|PDB:1K8B"
FT   STRAND          46..49
FT                   /evidence="ECO:0007829|PDB:1K8B"
FT   HELIX           52..60
FT                   /evidence="ECO:0007829|PDB:1K8B"
FT   HELIX           63..74
FT                   /evidence="ECO:0007829|PDB:1K8B"
FT   STRAND          75..81
FT                   /evidence="ECO:0007829|PDB:1K8B"
FT   STRAND          84..88
FT                   /evidence="ECO:0007829|PDB:1K8B"
FT   STRAND          111..113
FT                   /evidence="ECO:0007829|PDB:1K81"
FT   STRAND          117..123
FT                   /evidence="ECO:0007829|PDB:1K81"
FT   STRAND          126..132
FT                   /evidence="ECO:0007829|PDB:1K81"
FT   TURN            133..135
FT                   /evidence="ECO:0007829|PDB:1K81"
FT   STRAND          136..140
FT                   /evidence="ECO:0007829|PDB:1K81"
SQ   SEQUENCE   143 AA;  16797 MW;  1762C47A953FEB25 CRC64;
     MSDLENIDYY DYKALLKRAR SQIPDYVFQK DRFELPEIEI LIEGNRTIIR NFRELAKAVN
     RDEEFFAKYL LKETGSAGNL EGGRLILQRR ISPELLKSRI NDFLREYVIC RECGKPDTKI
     IKEGRVHLLK CMACGAIRPI RMI