ID   IF2B_METLZ              Reviewed;         204 AA.
AC   A2SSW2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Translation initiation factor 2 subunit beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=aIF2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=eIF-2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
GN   Name=eif2b {ECO:0000255|HAMAP-Rule:MF_00232}; OrderedLocusNames=Mlab_1249;
OS   Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX   NCBI_TaxID=410358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43576 / DSM 4855 / Z;
RX   PubMed=21304657; DOI=10.4056/sigs.35575;
RA   Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL   Stand. Genomic Sci. 1:197-203(2009).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00232}.
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DR   EMBL; CP000559; ABN07418.1; -; Genomic_DNA.
DR   RefSeq; WP_011833621.1; NC_008942.1.
DR   AlphaFoldDB; A2SSW2; -.
DR   SMR; A2SSW2; -.
DR   STRING; 410358.Mlab_1249; -.
DR   EnsemblBacteria; ABN07418; ABN07418; Mlab_1249.
DR   GeneID; 4794955; -.
DR   KEGG; mla:Mlab_1249; -.
DR   eggNOG; arCOG01640; Archaea.
DR   HOGENOM; CLU_026663_3_0_2; -.
DR   OrthoDB; 73843at2157; -.
DR   Proteomes; UP000000365; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002792; TRAM_dom.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; PTHR23001; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   Pfam; PF01938; TRAM; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   TIGRFAMs; TIGR00311; aIF-2beta; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..204
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_1000021649"
FT   DOMAIN          146..204
FT                   /note="TRAM"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00232"
SQ   SEQUENCE   204 AA;  22632 MW;  4C8AA63E73017A08 CRC64;
     MVQSYEDMLK AAYSGIGEPT ETGERFVMPK AKIYIEGKTT VLENFSDIVD SLNRDKDHFM
     KFILGELGTA GKIDGNRAVF NGKFEQAQFD AILETYVGDY VICSECGRPD TKLVKDDRVL
     MLLCEACGSK RPIRKRKAKT EVQGPAIEEG KELEVHIESI SKKGDGVARI GKYILYVAGT
     KAGQNVKVRI TRISGQVAFT QKIL