ID   IF2B_METMJ              Reviewed;         205 AA.
AC   A3CXJ3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Translation initiation factor 2 subunit beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=aIF2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=eIF-2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
GN   Name=eif2b {ECO:0000255|HAMAP-Rule:MF_00232}; OrderedLocusNames=Memar_2170;
OS   Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX   NCBI_TaxID=368407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35101 / DSM 1498 / JR1;
RX   PubMed=21304656; DOI=10.4056/sigs.32535;
RA   Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C.,
RA   Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981
RT   type strain JR1.";
RL   Stand. Genomic Sci. 1:189-196(2009).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00232}.
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DR   EMBL; CP000562; ABN58093.1; -; Genomic_DNA.
DR   RefSeq; WP_011845002.1; NC_009051.1.
DR   AlphaFoldDB; A3CXJ3; -.
DR   SMR; A3CXJ3; -.
DR   STRING; 368407.Memar_2170; -.
DR   EnsemblBacteria; ABN58093; ABN58093; Memar_2170.
DR   GeneID; 4846365; -.
DR   KEGG; mem:Memar_2170; -.
DR   eggNOG; arCOG01640; Archaea.
DR   HOGENOM; CLU_026663_3_0_2; -.
DR   OMA; GKPDTRL; -.
DR   OrthoDB; 73843at2157; -.
DR   Proteomes; UP000002146; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002792; TRAM_dom.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; PTHR23001; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   TIGRFAMs; TIGR00311; aIF-2beta; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..205
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_1000021652"
FT   DOMAIN          147..205
FT                   /note="TRAM"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00232"
SQ   SEQUENCE   205 AA;  22818 MW;  32D1E9EEE9BB6DDB CRC64;
     MSPSYEDLLK KAYTNITEPT EFEDRFTVPT ARAFIEGKTT VLENFAEIAS TLRREQDHLM
     KHLLGELGTA GKVEGTRAVF SGKFEQEQIN TIIKGYVDDY VICSECGKPD TRLVKTERVL
     TLKCDACGGH RPVRKRKAIV DPSAASKPTE GAIMDVTPQF LSKRGDGVVK IDRYTMYVAN
     AKPGQTVKIK ITRIAGTIIF TERVD