ID   IF2B_PICTO              Reviewed;         205 AA.
AC   Q6L0E6;
DT   21-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Translation initiation factor 2 subunit beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=aIF2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=eIF-2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
GN   Name=eif2b {ECO:0000255|HAMAP-Rule:MF_00232}; OrderedLocusNames=PTO0971;
OS   Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC
OS   100828).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Picrophilaceae; Picrophilus.
OX   NCBI_TaxID=263820;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828;
RX   PubMed=15184674; DOI=10.1073/pnas.0401356101;
RA   Fuetterer O., Angelov A., Liesegang H., Gottschalk G., Schleper C.,
RA   Schepers B., Dock C., Antranikian G., Liebl W.;
RT   "Genome sequence of Picrophilus torridus and its implications for life
RT   around pH 0.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096(2004).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00232}.
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DR   EMBL; AE017261; AAT43556.1; -; Genomic_DNA.
DR   RefSeq; WP_011177772.1; NC_005877.1.
DR   AlphaFoldDB; Q6L0E6; -.
DR   SMR; Q6L0E6; -.
DR   STRING; 263820.PTO0971; -.
DR   EnsemblBacteria; AAT43556; AAT43556; PTO0971.
DR   GeneID; 2845210; -.
DR   KEGG; pto:PTO0971; -.
DR   eggNOG; arCOG01640; Archaea.
DR   HOGENOM; CLU_026663_3_0_2; -.
DR   OMA; GKPDTRL; -.
DR   OrthoDB; 73843at2157; -.
DR   Proteomes; UP000000438; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002792; TRAM_dom.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; PTHR23001; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   Pfam; PF01938; TRAM; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..205
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_0000137427"
FT   DOMAIN          145..203
FT                   /note="TRAM"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00232"
SQ   SEQUENCE   205 AA;  23266 MW;  5BF3E104D64EA5C6 CRC64;
     MNFDYNKLLE RASGVLSSKT KNESRLKIPE PDVIYEGKST IIRNFIDITE MMNRDPEDVI
     KYLTKEFGIG AVLSGQRLII NRKVSEDEIQ SKMNEYMATY VICYECKSPD TEIQKIGRTY
     LLVCKACGAQ HPIRSNREII ENSNGIEIGK EYTVTIESTG SAGEGIARYQ GYTIYVPKAK
     KGERVKIIIR KIKRNVAIAE LADKK