ID   IF2B_PYRAB              Reviewed;         140 AA.
AC   Q9UYR6; G8ZIK4;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Translation initiation factor 2 subunit beta;
DE   AltName: Full=aIF2-beta;
DE   AltName: Full=eIF-2-beta;
GN   Name=eif2b; OrderedLocusNames=PYRAB14410; ORFNames=PAB0959;
OS   Pyrococcus abyssi (strain GE5 / Orsay).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=272844;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay;
RX   PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA   Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA   Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic archaeon
RT   Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GE5 / Orsay;
RX   PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA   Gao J., Wang J.;
RT   "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT   Pyrococcus furiosus DSM 3638.";
RL   Curr. Microbiol. 64:118-129(2012).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000305}.
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DR   EMBL; AJ248287; CAB50346.1; -; Genomic_DNA.
DR   EMBL; HE613800; CCE70887.1; -; Genomic_DNA.
DR   PIR; E75056; E75056.
DR   RefSeq; WP_010868556.1; NC_000868.1.
DR   AlphaFoldDB; Q9UYR6; -.
DR   SMR; Q9UYR6; -.
DR   STRING; 272844.PAB0959; -.
DR   EnsemblBacteria; CAB50346; CAB50346; PAB0959.
DR   GeneID; 1495716; -.
DR   KEGG; pab:PAB0959; -.
DR   PATRIC; fig|272844.11.peg.1532; -.
DR   eggNOG; arCOG01640; Archaea.
DR   HOGENOM; CLU_026663_3_1_2; -.
DR   OMA; NVKHHKS; -.
DR   OrthoDB; 96453at2157; -.
DR   PhylomeDB; Q9UYR6; -.
DR   Proteomes; UP000000810; Chromosome.
DR   Proteomes; UP000009139; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; PTHR23001; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   TIGRFAMs; TIGR00311; aIF-2beta; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..140
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_0000137428"
SQ   SEQUENCE   140 AA;  16247 MW;  9D40F2C556DB539A CRC64;
     MEIDYYDYEK LLEKAYEELP ENVKHHKSRF EVPGALVTIE GNKTIIENFK DIAEALNRDP
     QHLLKFLLRE IATAGTLEGK RVVLQGRFTP YLIANKIKKY IKEYVICPVC GSPDTKIIKR
     DRFYFLKCEA CGAETPIQHL