IF2B_SULIM
ID IF2B_SULIM Reviewed; 139 AA.
AC C3MU32;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 25-MAY-2022, entry version 56.
DE RecName: Full=Translation initiation factor 2 subunit beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE AltName: Full=aIF2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE AltName: Full=eIF-2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
GN Name=eif2b {ECO:0000255|HAMAP-Rule:MF_00232}; OrderedLocusNames=M1425_0175;
OS Sulfolobus islandicus (strain M.14.25 / Kamchatka #1).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=427317;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M.14.25 / Kamchatka #1;
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC forming a ternary complex with GTP and initiator tRNA.
CC {ECO:0000255|HAMAP-Rule:MF_00232}.
CC -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC {ECO:0000255|HAMAP-Rule:MF_00232}.
CC -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000255|HAMAP-
CC Rule:MF_00232}.
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DR EMBL; CP001400; ACP37066.1; -; Genomic_DNA.
DR RefSeq; WP_012710353.1; NC_012588.1.
DR AlphaFoldDB; C3MU32; -.
DR SMR; C3MU32; -.
DR EnsemblBacteria; ACP37066; ACP37066; M1425_0175.
DR GeneID; 7813868; -.
DR GeneID; 7940060; -.
DR GeneID; 8760019; -.
DR KEGG; sia:M1425_0175; -.
DR HOGENOM; CLU_026663_3_1_2; -.
DR OMA; GKPDTRL; -.
DR Proteomes; UP000001350; Chromosome.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00232; eIF_2_beta; 1.
DR InterPro; IPR045196; IF2/IF5.
DR InterPro; IPR004458; TIF2_bsu_arc.
DR InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR PANTHER; PTHR23001; PTHR23001; 1.
DR Pfam; PF01873; eIF-5_eIF-2B; 1.
DR SMART; SM00653; eIF2B_5; 1.
DR SUPFAM; SSF100966; SSF100966; 1.
DR SUPFAM; SSF75689; SSF75689; 1.
PE 3: Inferred from homology;
KW Initiation factor; Protein biosynthesis.
FT CHAIN 1..139
FT /note="Translation initiation factor 2 subunit beta"
FT /id="PRO_1000204380"
SQ SEQUENCE 139 AA; 15938 MW; 9A146D6E09F90867 CRC64;
MSSEKEYVEM LDRLYSKLPE KGRKEGTQAL PNLIIFNIGN TTMIRNFAEY CDRIRREDKI
CMKYLLKELA APGNVDDKGE LIIQGKFSSQ VINTLMERFL KAYVECSTCK SLDTVLKKEK
KSWYIVCLAC GAQTPVKPL