ID   IF2B_THEKO              Reviewed;         142 AA.
AC   Q5JIT0;
DT   21-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Translation initiation factor 2 subunit beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=aIF2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=eIF-2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
GN   Name=eif2b {ECO:0000255|HAMAP-Rule:MF_00232}; OrderedLocusNames=TK1621;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00232}.
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DR   EMBL; AP006878; BAD85810.1; -; Genomic_DNA.
DR   RefSeq; WP_011250572.1; NC_006624.1.
DR   AlphaFoldDB; Q5JIT0; -.
DR   SMR; Q5JIT0; -.
DR   STRING; 69014.TK1621; -.
DR   EnsemblBacteria; BAD85810; BAD85810; TK1621.
DR   GeneID; 3234140; -.
DR   KEGG; tko:TK1621; -.
DR   PATRIC; fig|69014.16.peg.1580; -.
DR   eggNOG; arCOG01640; Archaea.
DR   HOGENOM; CLU_026663_3_1_2; -.
DR   InParanoid; Q5JIT0; -.
DR   OMA; NVKHHKS; -.
DR   OrthoDB; 96453at2157; -.
DR   PhylomeDB; Q5JIT0; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IBA:GO_Central.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; PTHR23001; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   TIGRFAMs; TIGR00311; aIF-2beta; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..142
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_0000137432"
SQ   SEQUENCE   142 AA;  16301 MW;  D4CC9B7DBAA05473 CRC64;
     MSEKVDFYDF EKLLDKAYEE LPENVKHHHS RFEVPPAQVT IAGNRTIIEN FVDIAEAMNR
     DPNHLLKFIL REVATAGTLE GRRAILQGRF TPYLIANKMK KYLKEFVICP VCGSPDTKII
     KKGRFHFLKC EACGAETPIQ HL