ID   IF2B_THEVO              Reviewed;         208 AA.
AC   Q97B05;
DT   10-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2002, sequence version 2.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Translation initiation factor 2 subunit beta;
DE   AltName: Full=aIF2-beta;
DE   AltName: Full=eIF-2-beta;
GN   Name=eif2b; OrderedLocusNames=TV0654; ORFNames=TVG0649580;
OS   Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS   15438 / GSS1).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1;
RX   PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA   Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA   Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA   Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT   "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT   Thermoplasma volcanium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB59796.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000011; BAB59796.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_010916913.1; NC_002689.2.
DR   AlphaFoldDB; Q97B05; -.
DR   SMR; Q97B05; -.
DR   STRING; 273116.14324870; -.
DR   EnsemblBacteria; BAB59796; BAB59796; BAB59796.
DR   GeneID; 1441761; -.
DR   KEGG; tvo:TVG0649580; -.
DR   eggNOG; arCOG01640; Archaea.
DR   HOGENOM; CLU_026663_3_0_2; -.
DR   OMA; GKPDTRL; -.
DR   OrthoDB; 73843at2157; -.
DR   PhylomeDB; Q97B05; -.
DR   Proteomes; UP000001017; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002792; TRAM_dom.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; PTHR23001; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   Pfam; PF01938; TRAM; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..208
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_0000137437"
FT   DOMAIN          144..202
FT                   /note="TRAM"
SQ   SEQUENCE   208 AA;  23524 MW;  519A6594425CB7E5 CRC64;
     MTDSYDKLLE KAKDVLSSST KNIDRLKIPE PEIIREGKAT IIRNFQDIID IINRDPDQVI
     KFLTRELGTN IVQNGRRLII NKKVTLEELQ EKMNEYINTY VRCYECGSLD TEIQKSGRVS
     LLVCKACGAQ HPIHTVKEFK EEEGIEEGKE YTVEISEVGS SGEGRASFRG FTIFVPGTKK
     GETVKVKIKK IKNDVAIAEV VSRTSDKK