APEB_PSEU2
ID APEB_PSEU2 Reviewed; 429 AA.
AC Q4ZW15;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Probable M18 family aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_00467};
DE EC=3.4.11.- {ECO:0000255|HAMAP-Rule:MF_00467};
GN Name=apeB {ECO:0000255|HAMAP-Rule:MF_00467}; OrderedLocusNames=Psyr_1609;
OS Pseudomonas syringae pv. syringae (strain B728a).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX NCBI_TaxID=205918;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B728a;
RX PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA Kyrpides N.C., Ivanova N., Lindow S.E.;
RT "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT syringae B728a and pv. tomato DC3000.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00467};
CC -!- SIMILARITY: Belongs to the peptidase M18 family. {ECO:0000255|HAMAP-
CC Rule:MF_00467}.
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DR EMBL; CP000075; AAY36657.1; -; Genomic_DNA.
DR RefSeq; WP_011267127.1; NC_007005.1.
DR RefSeq; YP_234695.1; NC_007005.1.
DR AlphaFoldDB; Q4ZW15; -.
DR SMR; Q4ZW15; -.
DR STRING; 205918.Psyr_1609; -.
DR EnsemblBacteria; AAY36657; AAY36657; Psyr_1609.
DR KEGG; psb:Psyr_1609; -.
DR PATRIC; fig|205918.7.peg.1643; -.
DR eggNOG; COG1362; Bacteria.
DR HOGENOM; CLU_019532_2_0_6; -.
DR OMA; GPILKVN; -.
DR Proteomes; UP000000426; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.250.10; -; 1.
DR HAMAP; MF_00467; Aminopeptidase_M18_2; 1.
DR InterPro; IPR022984; M18_aminopeptidase_2.
DR InterPro; IPR001948; Peptidase_M18.
DR InterPro; IPR023358; Peptidase_M18_dom2.
DR PANTHER; PTHR28570; PTHR28570; 1.
DR Pfam; PF02127; Peptidase_M18; 1.
DR PRINTS; PR00932; AMINO1PTASE.
PE 3: Inferred from homology;
KW Aminopeptidase; Hydrolase; Metal-binding; Metalloprotease; Protease; Zinc.
FT CHAIN 1..429
FT /note="Probable M18 family aminopeptidase 2"
FT /id="PRO_1000013707"
FT BINDING 82
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00467"
FT BINDING 156
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00467"
FT BINDING 401
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00467"
SQ SEQUENCE 429 AA; 46708 MW; 396763ED4FAF2D61 CRC64;
MRAELNKGLI DFLKASPTPF HATATLVQHF EAAGFQRLDE RDTWAVETGG RYFVTRNDSS
IVAFRMGRQS PLSGGIRMVG AHTDSPCLRV KPQPELQRQG FWQLGVEVYG GALLAPWFDR
DLSLAGRVTF RRDGKVESQL IDFKLPIAVI PNLAIHLNRT ANEGWAINAQ NELPPILAQV
AGDERADFRA LLTDQLAREH GLNADVVLDY ELSFYDTQGA AVVGLNGDFL AGARLDNLLS
CFAGMQALLN TESDETALLV CTDHEEVGSS SACGADGAML EQIVQRLLPS SEDYVRTIQK
SLLISADNAH GIHPNYADKH DANHGPKLNA GPVIKVNSNQ RYATNSETAG FFRHLCMAEE
VPVQSFVVRS DMGCGSTIGP ITASHLGIRT VDIGLPTFAM HSIRELAGSH DLAHLVKVLS
AFYASHELP