ID   IF3_CERS4               Reviewed;         181 AA.
AC   O33567; Q3J546;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Translation initiation factor IF-3 {ECO:0000255|HAMAP-Rule:MF_00080};
GN   Name=infC {ECO:0000255|HAMAP-Rule:MF_00080}; Synonyms=pifC;
GN   OrderedLocusNames=RHOS4_05200; ORFNames=RSP_1937;
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=272943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9370368; DOI=10.1111/j.1432-1033.1997.t01-1-00564.x;
RA   Babic S., Hunter C.N., Rakhlin N.J., Simons R.W., Phillips-Jones M.K.;
RT   "Molecular characterisation of the pifC gene encoding translation
RT   initiation factor 3, which is required for normal photosynthetic complex
RT   formation in Rhodobacter sphaeroides NCIB 8253.";
RL   Eur. J. Biochem. 249:564-575(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC   / NCIMB 8253 / ATH 2.4.1.;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA   Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the
CC       equilibrum between 70S ribosomes and their 50S and 30S subunits in
CC       favor of the free subunits, thus enhancing the availability of 30S
CC       subunits on which protein synthesis initiation begins.
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00080}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the IF-3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00080}.
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DR   EMBL; Y14733; CAA75028.1; -; Genomic_DNA.
DR   EMBL; CP000143; ABA78088.2; -; Genomic_DNA.
DR   RefSeq; WP_023003529.1; NZ_CP030271.1.
DR   RefSeq; YP_351989.2; NC_007493.2.
DR   AlphaFoldDB; O33567; -.
DR   SMR; O33567; -.
DR   STRING; 272943.RSP_1937; -.
DR   EnsemblBacteria; ABA78088; ABA78088; RSP_1937.
DR   GeneID; 57469283; -.
DR   GeneID; 67445731; -.
DR   KEGG; rsp:RSP_1937; -.
DR   PATRIC; fig|272943.9.peg.830; -.
DR   eggNOG; COG0290; Bacteria.
DR   OMA; RNMIMFL; -.
DR   Proteomes; UP000002703; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.10.20.80; -; 1.
DR   Gene3D; 3.30.110.10; -; 1.
DR   HAMAP; MF_00080; IF_3; 1.
DR   InterPro; IPR036788; T_IF-3_C_sf.
DR   InterPro; IPR036787; T_IF-3_N_sf.
DR   InterPro; IPR019813; Translation_initiation_fac3_CS.
DR   InterPro; IPR001288; Translation_initiation_fac_3.
DR   InterPro; IPR019815; Translation_initiation_fac_3_C.
DR   InterPro; IPR019814; Translation_initiation_fac_3_N.
DR   PANTHER; PTHR10938; PTHR10938; 1.
DR   Pfam; PF00707; IF3_C; 1.
DR   Pfam; PF05198; IF3_N; 1.
DR   SUPFAM; SSF54364; SSF54364; 1.
DR   SUPFAM; SSF55200; SSF55200; 1.
DR   TIGRFAMs; TIGR00168; infC; 1.
DR   PROSITE; PS00938; IF3; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..181
FT                   /note="Translation initiation factor IF-3"
FT                   /id="PRO_0000177566"
SQ   SEQUENCE   181 AA;  20541 MW;  36B720F3BB21BEF4 CRC64;
     MARRPHNAPP QRETGPRVNE RIRCPEVRLI GANGENIGVV TPSRAMMMAE EAGLDLVEIS
     PNAEPPVCKI MDFGKFKYEQ QKREAEARKK QHIIEIKEIK FRPGTDTHDY DVKMRSVLKF
     LSEGDKVKVT LRFRGREMAH QELGLELLNR VAAHVSEAEA GKVEAMPKLE GRQMVMMIAP
     K