ID   IF3_MYCFE               Reviewed;         212 AA.
AC   Q05426;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Translation initiation factor IF-3 {ECO:0000255|HAMAP-Rule:MF_00080};
GN   Name=infC {ECO:0000255|HAMAP-Rule:MF_00080};
OS   Mycoplasmopsis fermentans (Mycoplasma fermentans).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasmopsis.
OX   NCBI_TaxID=2115;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Incognitus;
RX   PubMed=8486291; DOI=10.1016/0378-1119(93)90619-e;
RA   Hu W.S., Wang R.Y.-H., Shih J.W.-K., Lo S.-C.;
RT   "Identification of a putative infC-rpmI-rplT operon flanked by long
RT   inverted repeats in Mycoplasma fermentans (incognitus strain).";
RL   Gene 127:79-85(1993).
CC   -!- FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the
CC       equilibrum between 70S ribosomes and their 50S and 30S subunits in
CC       favor of the free subunits, thus enhancing the availability of 30S
CC       subunits on which protein synthesis initiation begins.
CC       {ECO:0000255|HAMAP-Rule:MF_00080}.
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00080}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00080}.
CC   -!- SIMILARITY: Belongs to the IF-3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00080}.
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DR   EMBL; M95046; AAA25413.1; -; Genomic_DNA.
DR   PIR; JN0653; JN0653.
DR   AlphaFoldDB; Q05426; -.
DR   SMR; Q05426; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.10.20.80; -; 1.
DR   Gene3D; 3.30.110.10; -; 1.
DR   HAMAP; MF_00080; IF_3; 1.
DR   InterPro; IPR036788; T_IF-3_C_sf.
DR   InterPro; IPR036787; T_IF-3_N_sf.
DR   InterPro; IPR019813; Translation_initiation_fac3_CS.
DR   InterPro; IPR001288; Translation_initiation_fac_3.
DR   InterPro; IPR019815; Translation_initiation_fac_3_C.
DR   InterPro; IPR019814; Translation_initiation_fac_3_N.
DR   PANTHER; PTHR10938; PTHR10938; 1.
DR   Pfam; PF00707; IF3_C; 1.
DR   Pfam; PF05198; IF3_N; 1.
DR   SUPFAM; SSF54364; SSF54364; 1.
DR   SUPFAM; SSF55200; SSF55200; 1.
DR   TIGRFAMs; TIGR00168; infC; 1.
DR   PROSITE; PS00938; IF3; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Initiation factor; Protein biosynthesis.
FT   CHAIN           1..212
FT                   /note="Translation initiation factor IF-3"
FT                   /id="PRO_0000177540"
FT   REGION          190..212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   212 AA;  24486 MW;  F25327F201F70E30 CRC64;
     MQPQGKMKKP TAEHMINENI PFQKVFVIGA NGEKVGVLST REAIEMAKEQ RLDLVLISVQ
     PKPIARILDY GKFKYERKKK QKAAKEKQTV IQNRQIRLTP LIGEHDLNVK ARKAKEFLLD
     GDRIKVSLKF RGRESARPEL GHKTLEKFYK AVEDLADIAK EAELVNDRFL DMYLQPNKIK
     VNKYRKEHNL VDKNSDSQDK SVSEEDTNEG EQ