IF3_SHEON
ID IF3_SHEON Reviewed; 180 AA.
AC Q8EER8;
DT 28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2013, sequence version 3.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Translation initiation factor IF-3 {ECO:0000255|HAMAP-Rule:MF_00080};
GN Name=infC {ECO:0000255|HAMAP-Rule:MF_00080}; OrderedLocusNames=SO_2300;
OS Shewanella oneidensis (strain MR-1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=211586;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1;
RX PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A.,
RA Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J.,
RA Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J.,
RA Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V.,
RA Smith H.O., Venter J.C., Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
CC -!- FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the
CC equilibrum between 70S ribosomes and their 50S and 30S subunits in
CC favor of the free subunits, thus enhancing the availability of 30S
CC subunits on which protein synthesis initiation begins.
CC {ECO:0000255|HAMAP-Rule:MF_00080}.
CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00080}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00080}.
CC -!- SIMILARITY: Belongs to the IF-3 family. {ECO:0000255|HAMAP-
CC Rule:MF_00080}.
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DR EMBL; AE014299; AAN55340.2; -; Genomic_DNA.
DR RefSeq; NP_717896.2; NC_004347.2.
DR RefSeq; WP_011072302.1; NZ_CP053946.1.
DR AlphaFoldDB; Q8EER8; -.
DR SMR; Q8EER8; -.
DR STRING; 211586.SO_2300; -.
DR PaxDb; Q8EER8; -.
DR GeneID; 58509587; -.
DR KEGG; son:SO_2300; -.
DR PATRIC; fig|211586.12.peg.2215; -.
DR eggNOG; COG0290; Bacteria.
DR HOGENOM; CLU_054919_3_2_6; -.
DR OrthoDB; 1760144at2; -.
DR PhylomeDB; Q8EER8; -.
DR BioCyc; SONE211586:G1GMP-2102-MON; -.
DR Proteomes; UP000008186; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0043022; F:ribosome binding; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR GO; GO:0032790; P:ribosome disassembly; IBA:GO_Central.
DR Gene3D; 3.10.20.80; -; 1.
DR Gene3D; 3.30.110.10; -; 1.
DR HAMAP; MF_00080; IF_3; 1.
DR InterPro; IPR036788; T_IF-3_C_sf.
DR InterPro; IPR036787; T_IF-3_N_sf.
DR InterPro; IPR019813; Translation_initiation_fac3_CS.
DR InterPro; IPR001288; Translation_initiation_fac_3.
DR InterPro; IPR019815; Translation_initiation_fac_3_C.
DR InterPro; IPR019814; Translation_initiation_fac_3_N.
DR PANTHER; PTHR10938; PTHR10938; 1.
DR Pfam; PF00707; IF3_C; 1.
DR Pfam; PF05198; IF3_N; 1.
DR SUPFAM; SSF54364; SSF54364; 1.
DR SUPFAM; SSF55200; SSF55200; 1.
DR TIGRFAMs; TIGR00168; infC; 1.
DR PROSITE; PS00938; IF3; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome.
FT CHAIN 1..180
FT /note="Translation initiation factor IF-3"
FT /id="PRO_0000177573"
SQ SEQUENCE 180 AA; 20395 MW; 83B0AC8A4559D48B CRC64;
MKIKKTAGRQ LAPNRINEEI TGVPEVRLTG IDGEAIGVVS IRDAQNLADE AGVDLVEISP
NAEPPVCRIM DYGKFLFDKA KSAKEQKKKQ KQVQVKEIKF RPGTDENDYQ VKLRNLIRFL
EDGDKAKITL RFRGREMAHQ NLGMDLLNRI KTDLDEYAVV ESFPKMEGRQ AIMVLAPKKK