IF43A_SALSA
ID IF43A_SALSA Reviewed; 207 AA.
AC B5XBI1;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 03-AUG-2022, entry version 28.
DE RecName: Full=Intraflagellar transport protein 43 homolog A;
GN Name=ift43a;
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
CC -!- FUNCTION: Component of IFT complex A (IFT-A) involved in retrograde
CC ciliary transport along microtubules from the ciliary tip to the base.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of IFT complex A. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IFT43 family. {ECO:0000305}.
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DR EMBL; BT048400; ACI68201.1; -; mRNA.
DR RefSeq; XP_014066354.1; XM_014210879.1.
DR AlphaFoldDB; B5XBI1; -.
DR GeneID; 106611048; -.
DR KEGG; sasa:106611048; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR Bgee; ENSSSAG00000055332; Expressed in semen and 16 other tissues.
DR GO; GO:0005929; C:cilium; IEA:GOC.
DR GO; GO:0030991; C:intraciliary transport particle A; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; ISS:UniProtKB.
DR GO; GO:0035721; P:intraciliary retrograde transport; ISS:UniProtKB.
DR InterPro; IPR029302; IFT43.
DR PANTHER; PTHR33724; PTHR33724; 1.
DR Pfam; PF15305; IFT43; 1.
PE 2: Evidence at transcript level;
KW Cilium biogenesis/degradation; Reference proteome.
FT CHAIN 1..207
FT /note="Intraflagellar transport protein 43 homolog A"
FT /id="PRO_0000409497"
FT REGION 1..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 207 AA; 23140 MW; F357CAE8271E48C8 CRC64;
MDDNLQLGDS GVVKNVAKLG RRARLAAEQT SSLEESRHVR KSSSSTSMGE VPPPKPARRQ
GGWAEETSGS AKSGRRPAVV EDVEDRRLRP QTPQGSDDEG DIPVIPDLDE VQEEDLTMQV
AAPPSIQVNR VMTYRDLDND LMKYSAFQTL DGEIDLKLLT KVLAPEQEVR EEDVGWDWDR
LFTEVSSELL TEWDQGEKEE QVPLPVL