IF4G1_ORYSJ
ID IF4G1_ORYSJ Reviewed; 793 AA.
AC Q84PB3; Q0JC04; Q7XT80;
DT 09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2013, sequence version 2.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Eukaryotic translation initiation factor isoform 4G-1;
DE Short=eIF(iso)-4G-1;
DE Short=eIF(iso)4G-1;
DE AltName: Full=Eukaryotic initiation factor iso-4F subunit p82;
DE Short=eIF-(iso)4F p82 subunit;
GN OrderedLocusNames=Os04g0499300, LOC_Os04g42140; ORFNames=OSJNBa0029H02.9;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12684538; DOI=10.1073/pnas.0737574100;
RA Cooper B., Clarke J.D., Budworth P., Kreps J., Hutchison D., Park S.,
RA Guimil S., Dunn M., Luginbuehl P., Ellero C., Goff S.A., Glazebrook J.;
RT "A network of rice genes associated with stress response and seed
RT development.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:4945-4950(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP DISRUPTION PHENOTYPE, AND FUNCTION.
RX PubMed=16774645; DOI=10.1111/j.1365-313x.2006.02792.x;
RA Albar L., Bangratz-Reyser M., Hebrard E., Ndjiondjop M.N., Jones M.,
RA Ghesquiere A.;
RT "Mutations in the eIF(iso)4G translation initiation factor confer high
RT resistance of rice to Rice yellow mottle virus.";
RL Plant J. 47:417-426(2006).
RN [7]
RP GENE FAMILY.
RX PubMed=17898986; DOI=10.1007/s00122-007-0646-6;
RA Boisnard A., Albar L., Thiemele D., Rondeau M., Ghesquiere A.;
RT "Evaluation of genes from eIF4E and eIF4G multigenic families as potential
RT candidates for partial resistance QTLs to Rice yellow mottle virus in
RT rice.";
RL Theor. Appl. Genet. 116:53-62(2007).
CC -!- FUNCTION: Plays a role in the accumulation of a sobemovirus (RYMV)
CC during viral infection. {ECO:0000269|PubMed:16774645}.
CC -!- SUBUNIT: EIF4F is a multi-subunit complex, the composition of which
CC varies with external and internal environmental conditions. It is
CC composed of at least EIF4A, EIF4E and EIF4G. In higher plants two
CC isoforms of EIF4F have been identified, named isoform EIF4F and isoform
CC EIF(iso)4F. Isoform EIF4F has subunits p220 and p26, whereas isoform
CC EIF(iso)4F has subunits p82 and p28.
CC -!- DISRUPTION PHENOTYPE: Displays resistance to rice yellow mottle virus
CC (RYMV) infection. {ECO:0000269|PubMed:16774645}.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF15133.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAE01628.3; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY224450; AAO72569.1; -; mRNA.
DR EMBL; AL606594; CAE01628.3; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008210; BAF15133.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015635639.1; XM_015780153.1.
DR AlphaFoldDB; Q84PB3; -.
DR SMR; Q84PB3; -.
DR IntAct; Q84PB3; 1.
DR STRING; 4530.OS04T0499300-01; -.
DR PaxDb; Q84PB3; -.
DR PRIDE; Q84PB3; -.
DR GeneID; 4336300; -.
DR KEGG; osa:4336300; -.
DR eggNOG; KOG0401; Eukaryota.
DR HOGENOM; CLU_021872_0_0_1; -.
DR InParanoid; Q84PB3; -.
DR OrthoDB; 594395at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; Q84PB3; OS.
DR GO; GO:0016281; C:eukaryotic translation initiation factor 4F complex; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; PTHR23253; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; SSF48371; 2.
DR PROSITE; PS51366; MI; 1.
PE 2: Evidence at transcript level;
KW Initiation factor; Protein biosynthesis; Reference proteome;
KW Translation regulation.
FT CHAIN 1..793
FT /note="Eukaryotic translation initiation factor isoform 4G-
FT 1"
FT /id="PRO_0000420545"
FT DOMAIN 208..435
FT /note="MIF4G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00698"
FT DOMAIN 627..749
FT /note="MI"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00698"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 84..86
FT /note="RIN -> IK (in Ref. 1; AAO72569)"
FT /evidence="ECO:0000305"
FT CONFLICT 456
FT /note="M -> I (in Ref. 1; AAO72569)"
FT /evidence="ECO:0000305"
FT CONFLICT 590
FT /note="L -> P (in Ref. 1; AAO72569)"
FT /evidence="ECO:0000305"
FT CONFLICT 692
FT /note="A -> T (in Ref. 1; AAO72569)"
FT /evidence="ECO:0000305"
FT CONFLICT 738
FT /note="G -> S (in Ref. 1; AAO72569)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 793 AA; 87022 MW; 38C935BCA33E297F CRC64;
MEKDHQPVIS LRPGGGGGGP RPGRLFSPAF AAAASGSGDL LRSHVGGASK IGDPNFEVRE
RVRYTRDQLL ELREIVDIPE AILRINQEID IELHGEDQIW GRPESDVQVQ TQTQAQPHNR
YGETDNRDWR ARTVQPPAAN EEKSWDNIRE AKAAHASSGR QQEQVNRQDQ LNHQFASKAQ
VGPTPALIKA EVPWSARRGN LSEKDRVLKT VKGILNKLTP EKFDLLKGQL MESGITTADI
LKDVISLIFE KAVFEPTFCP MYAQLCSDLN EKLPSFPSEE PGGKEITFKR VLLNNCQEAF
EGAESLRAEI AKLTGPDQEM ERRDKERIVK LRTLGNIRLI GELLKQKMVP EKIVHHIVQE
LLGSGPDKKA CPEEENVEAI CQFFNTIGKQ LDENPKSRRI NDTYFIQMKE LTTNLQLAPR
LRFMVRDVVD LRSNNWVPRR EEIKAKTISE IHDEAMKTLG LRPGATGLTR NGRNAPGGPL
SPGGFPMNRP GTGGMMPGMP GTPGMPGSRK MPGMPGLDND NWEVPRSKSM PRGDSLRNQG
PLLNKPSSIN KPSSINSRLL PHGSGALIGK SALLGSGGPP SRPSSLMASL THTPAQTAPS
PKPVSAAPAV VPVTDKAAGS SHEMPAAVQK KTVSLLEEYF GIRILDEAQQ CIEELQCPEY
YSEIVKEAIN LALDKGPNFI DPLVRLLEHL HAKKIFKTED LKTGCLLYAA LLEDIGIDLP
LAPALFGEVV ARLSLSCGLS FEVVEEILKA VEDTYFRKGI FDAVMKTMGG NSSGQAILSS
HAVVIDACNK LLK
