ID   IF6_HALS3               Reviewed;         220 AA.
AC   B0R7X7;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=OE_4458R;
OS   Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=478009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA   Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA   Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT   "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT   R1 compared to that of strain NRC-1.";
RL   Genomics 91:335-346(2008).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
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DR   EMBL; AM774415; CAP14846.1; -; Genomic_DNA.
DR   RefSeq; WP_010903842.1; NC_010364.1.
DR   AlphaFoldDB; B0R7X7; -.
DR   SMR; B0R7X7; -.
DR   EnsemblBacteria; CAP14846; CAP14846; OE_4458R.
DR   GeneID; 5954088; -.
DR   GeneID; 62887706; -.
DR   KEGG; hsl:OE_4458R; -.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   PhylomeDB; B0R7X7; -.
DR   Proteomes; UP000001321; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   CDD; cd00527; IF6; 1.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..220
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_1000090393"
SQ   SEQUENCE   220 AA;  22328 MW;  E8BD3A92C136021F CRC64;
     MLRAAFRGSA YIGVFARATE SCVLVRPDLD DDFVDSIADE LGVPAVQTTV GGSSTVGSLA
     AGNSSGLLVS NRIRERERDR IEAAGVTVGE LPGAVNAAGN VVVANDDGAY VHSGLSDDAV
     AAVEETLDVS ATRGQLAGVD TVGTAAVATT DGVLCHPKAT DAELERIEET LGVYADVGTV
     NYGAPLVGSG LVAADDGYLV GDDTTGPEIG RIEDTLGYIE