ID   IF6_HALWD               Reviewed;         226 AA.
AC   Q18EU8;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=HQ_3422A;
OS   Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloquadratum.
OX   NCBI_TaxID=362976;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16790 / HBSQ001;
RX   PubMed=16820047; DOI=10.1186/1471-2164-7-169;
RA   Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F.,
RA   Pfeiffer F., Oesterhelt D.;
RT   "The genome of the square archaeon Haloquadratum walsbyi: life at the
RT   limits of water activity.";
RL   BMC Genomics 7:169-169(2006).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
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DR   EMBL; AM180088; CAJ53519.1; -; Genomic_DNA.
DR   RefSeq; WP_011572616.1; NC_008212.1.
DR   AlphaFoldDB; Q18EU8; -.
DR   SMR; Q18EU8; -.
DR   STRING; 362976.HQ_3422A; -.
DR   EnsemblBacteria; CAJ53519; CAJ53519; HQ_3422A.
DR   GeneID; 4194787; -.
DR   KEGG; hwa:HQ_3422A; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   Proteomes; UP000001975; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..226
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_0000259427"
SQ   SEQUENCE   226 AA;  23284 MW;  8898BC95E5320E7B CRC64;
     MLRASFAGSP YVGVFARATD DVLLLRSDVD DDTADAMAAE LDIPAVATTI GGSGTVGALA
     TGNENGILVT SNVTMREKEA IETTASVSVT ELPGRINAAG NVILANDYGA YVHPDLSTEA
     VESIESALNV PVARGKLADV RTVGTAAVAT NRGVLCHPKA REPELEAIED HLDVRADIGT
     VNYGAPLVGS GIVAGQTGYV VGEDTTGPEL TRIEDTLGYL ESITSE