ID   IF6_HYPBU               Reviewed;         225 AA.
AC   A2BN57;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=Hbut_1599;
OS   Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Pyrodictiaceae;
OC   Hyperthermus.
OX   NCBI_TaxID=415426;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5456 / JCM 9403 / PLM1-5;
RX   PubMed=17350933; DOI=10.1155/2007/745987;
RA   Bruegger K., Chen L., Stark M., Zibat A., Redder P., Ruepp A., Awayez M.,
RA   She Q., Garrett R.A., Klenk H.-P.;
RT   "The genome of Hyperthermus butylicus: a sulfur-reducing, peptide
RT   fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.";
RL   Archaea 2:127-135(2007).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
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DR   EMBL; CP000493; ABM81418.1; -; Genomic_DNA.
DR   RefSeq; WP_011822736.1; NC_008818.1.
DR   AlphaFoldDB; A2BN57; -.
DR   SMR; A2BN57; -.
DR   STRING; 415426.Hbut_1599; -.
DR   EnsemblBacteria; ABM81418; ABM81418; Hbut_1599.
DR   GeneID; 4782004; -.
DR   KEGG; hbu:Hbut_1599; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   OrthoDB; 70525at2157; -.
DR   Proteomes; UP000002593; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..225
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_1000002595"
SQ   SEQUENCE   225 AA;  24553 MW;  9FAF12DE37DA688A CRC64;
     MIEYLNVHGN PNIGVYIYAN NKIALVPPTL TEKDKKKIEE TLGVEVIETK IADMIINGVM
     IAGNDNGLLL PRIVKPEELD YLREHIGDKV RLEILEVRQT ALGNLIAANN RGALVSPLID
     KAILDKIKSV LGVETIYQRH LANIPTVGSM IVVTNRGGVV HPGVSDDEIR ILNSVFGVEF
     TTATVNFGLY FVKAGLVAND HGALVGDETT GPELMRIQQA LRLRG