IF6_METB6
ID IF6_METB6 Reviewed; 220 AA.
AC A7I9I6;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=Mboo_1882;
OS Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanoregulaceae; Methanoregula.
OX NCBI_TaxID=456442;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21154 / JCM 14090 / 6A8;
RX PubMed=25998264; DOI=10.1099/mic.0.000117;
RA Braeuer S., Cadillo-Quiroz H., Kyrpides N., Woyke T., Goodwin L.,
RA Detter C., Podell S., Yavitt J.B., Zinder S.H.;
RT "Genome of Methanoregula boonei 6A8 reveals adaptations to oligotrophic
RT peatland environments.";
RL Microbiology 161:1572-1581(2015).
CC -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC association with the 30S ribosomal subunit to form the 70S initiation
CC complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC Rule:MF_00032}.
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DR EMBL; CP000780; ABS56397.1; -; Genomic_DNA.
DR RefSeq; WP_012107450.1; NC_009712.1.
DR AlphaFoldDB; A7I9I6; -.
DR SMR; A7I9I6; -.
DR STRING; 456442.Mboo_1882; -.
DR PRIDE; A7I9I6; -.
DR EnsemblBacteria; ABS56397; ABS56397; Mboo_1882.
DR GeneID; 5411376; -.
DR KEGG; mbn:Mboo_1882; -.
DR eggNOG; arCOG04176; Archaea.
DR HOGENOM; CLU_071894_1_0_2; -.
DR OMA; GEDTTGP; -.
DR OrthoDB; 70525at2157; -.
DR Proteomes; UP000002408; Chromosome.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR HAMAP; MF_00032; eIF_6; 1.
DR InterPro; IPR002769; eIF6.
DR PANTHER; PTHR10784; PTHR10784; 1.
DR Pfam; PF01912; eIF-6; 1.
DR PIRSF; PIRSF006413; IF-6; 1.
DR SMART; SM00654; eIF6; 1.
DR TIGRFAMs; TIGR00323; eIF-6; 1.
PE 3: Inferred from homology;
KW Initiation factor; Protein biosynthesis; Reference proteome.
FT CHAIN 1..220
FT /note="Translation initiation factor 6"
FT /id="PRO_1000002597"
SQ SEQUENCE 220 AA; 22633 MW; F1F10C5E3AD1EB07 CRC64;
MERTTTFAGD PNIGVFARVA GNIAVIPPEA PEEFRNAIRE GLGVELLVTT IQGSAIIGSL
VAGNSRGLVV SGLATDEELA VLKKHRKVML LCETMNAAGN VIMANDTFAA VHPDLPAEVA
EEIGAFLGVE VIHLTLGGVR TTGMAGVATN KGVIVHPRAT AQEIARLETV SGIPVGTGTI
NMGSGLVGTG LLVNDTGYLA GNATSGFELG RVEDVFGFLE