ID   IF6_METHJ               Reviewed;         221 AA.
AC   Q2FS97;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=Mhun_3020;
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1;
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
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DR   EMBL; CP000254; ABD42707.1; -; Genomic_DNA.
DR   RefSeq; WP_011449958.1; NC_007796.1.
DR   AlphaFoldDB; Q2FS97; -.
DR   SMR; Q2FS97; -.
DR   STRING; 323259.Mhun_3020; -.
DR   EnsemblBacteria; ABD42707; ABD42707; Mhun_3020.
DR   GeneID; 3922842; -.
DR   KEGG; mhu:Mhun_3020; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   OrthoDB; 70525at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..221
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_0000259431"
SQ   SEQUENCE   221 AA;  23654 MW;  24D7E3CADEC1F112 CRC64;
     MDRFVSIAGD PHIGVFTRVF DDIAVVPPDV PEEVTTRYEE ALKVEIVRTT IQRSPIIGSL
     LVGNNNGLVI TGMATEEEIA TLSEYRDLML LEEGMNAAGN IILANDHFAA VHPEMDEEFM
     DALSDFLKVP VIPLTLGDVK TVGMAAVATN SGVVVSPRTT PGEIQRLEQV CSLPVGKGTV
     TMGNAMVGTG LVANRYGYLA GVGTSGYELG RIEDILGFEE E