ID   IF6_METLZ               Reviewed;         222 AA.
AC   A2STI7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=Mlab_1478;
OS   Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX   NCBI_TaxID=410358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43576 / DSM 4855 / Z;
RX   PubMed=21304657; DOI=10.4056/sigs.35575;
RA   Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL   Stand. Genomic Sci. 1:197-203(2009).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
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DR   EMBL; CP000559; ABN07643.1; -; Genomic_DNA.
DR   RefSeq; WP_011833846.1; NC_008942.1.
DR   AlphaFoldDB; A2STI7; -.
DR   SMR; A2STI7; -.
DR   STRING; 410358.Mlab_1478; -.
DR   EnsemblBacteria; ABN07643; ABN07643; Mlab_1478.
DR   GeneID; 4795544; -.
DR   KEGG; mla:Mlab_1478; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   OrthoDB; 70525at2157; -.
DR   Proteomes; UP000000365; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..222
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_1000002598"
SQ   SEQUENCE   222 AA;  23440 MW;  A365E3FA1CDE9DB0 CRC64;
     MDPTLSLNGD PNIGVYARVF EDLAVVPVEA PKEFRDKIAE ALDVEVIETF VQGSSVIGLL
     LTGNSRGFVV SGLIQDSELE ILQEYGDCLL LGEEMNAAGN VILTNDSFAV VHPDMSSAMR
     EMVADFLKVK IIPMSFAGVG TVGMTCACTN TGVLLPARST PEEIEKLERS IDDANVAIGT
     GSVNMGSGLI GTGLLINSKG YLAGNATTGY ELGRIEDVFG FL