ID   IF6_METMP               Reviewed;         227 AA.
AC   Q6M156;
DT   10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=MMP0061;
OS   Methanococcus maripaludis (strain S2 / LL).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=267377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2 / LL;
RX   PubMed=15466049; DOI=10.1128/jb.186.20.6956-6969.2004;
RA   Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA   Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA   Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA   Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D.,
RA   Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA   Olson M.V., Leigh J.A.;
RT   "Complete genome sequence of the genetically tractable hydrogenotrophic
RT   methanogen Methanococcus maripaludis.";
RL   J. Bacteriol. 186:6956-6969(2004).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
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DR   EMBL; BX950229; CAF29617.1; -; Genomic_DNA.
DR   RefSeq; WP_011170005.1; NC_005791.1.
DR   AlphaFoldDB; Q6M156; -.
DR   SMR; Q6M156; -.
DR   STRING; 267377.MMP0061; -.
DR   EnsemblBacteria; CAF29617; CAF29617; MMP0061.
DR   GeneID; 41278470; -.
DR   KEGG; mmp:MMP0061; -.
DR   PATRIC; fig|267377.15.peg.62; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   OrthoDB; 70525at2157; -.
DR   BioCyc; MMAR267377:MMP_RS00355-MON; -.
DR   Proteomes; UP000000590; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..227
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_0000153749"
SQ   SEQUENCE   227 AA;  24595 MW;  9A3D921BDCBF8E2B CRC64;
     MIMKTYFSGV STLGVHSLAT EDYGFFPLSV DQKTMERMKN VLDIPATQLN ISNSSLIGSL
     CVGNSNGLLV PNITTEKELE LIKMFLKENS LDVNLERLKA KNTAFGNLIL TNNKGCIISE
     ELSRFRKTIE DVLDVESGVG NYAELPTVGS NGVATDKGCL VHPLTDELEL EWIQDILRVD
     YVERGTANRG VTSVGACILA NTKGAVVGGD TSGPEILKIE EALDLID