ID   IF6_METS3               Reviewed;         223 AA.
AC   A5UL31;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=Msm_0704;
OS   Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX   NCBI_TaxID=420247;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35061 / DSM 861 / OCM 144 / PS;
RX   PubMed=17563350; DOI=10.1073/pnas.0704189104;
RA   Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B.,
RA   Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.;
RT   "Genomic and metabolic adaptations of Methanobrevibacter smithii to the
RT   human gut.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
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DR   EMBL; CP000678; ABQ86909.1; -; Genomic_DNA.
DR   RefSeq; WP_004032461.1; NC_009515.1.
DR   AlphaFoldDB; A5UL31; -.
DR   SMR; A5UL31; -.
DR   STRING; 420247.Msm_0704; -.
DR   EnsemblBacteria; ABQ86909; ABQ86909; Msm_0704.
DR   GeneID; 5217273; -.
DR   KEGG; msi:Msm_0704; -.
DR   PATRIC; fig|420247.28.peg.701; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   Proteomes; UP000001992; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..223
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_1000002602"
SQ   SEQUENCE   223 AA;  23353 MW;  2113840BE0AF2B61 CRC64;
     MLRRINIVDN PNIGVFILAT DDLAVVPYNL LDEKVKLIEE TLEVDAVKSS ISGCNLIGSL
     AVANSNGIVV SPHVLDREVK QFEELGLNVA TIPGNYTAVG NIVAANDTGA IVSPFLSDEA
     VKVIEDTLDV NVESTSMVGS DIIGSLITVT NKGFLMDKNA TETEVDFARD VFGVEGDIGT
     VGRGISLVGA CSLANSSGAI VAKESTGPEM ARVEEALGFL DDL