IF6_NANEQ
ID IF6_NANEQ Reviewed; 208 AA.
AC Q74MW8;
DT 10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Translation initiation factor 6;
DE Short=aIF-6;
GN Name=eif6; OrderedLocusNames=NEQ517;
OS Nanoarchaeum equitans (strain Kin4-M).
OC Archaea; Nanoarchaeota; Candidatus Nanoarchaeia; Nanoarchaeales;
OC Nanoarchaeaceae; Nanoarchaeum.
OX NCBI_TaxID=228908;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Kin4-M;
RX PubMed=14566062; DOI=10.1073/pnas.1735403100;
RA Waters E., Hohn M.J., Ahel I., Graham D.E., Adams M.D., Barnstead M.,
RA Beeson K.Y., Bibbs L., Bolanos R., Keller M., Kretz K., Lin X., Mathur E.,
RA Ni J., Podar M., Richardson T., Sutton G.G., Simon M., Soell D.,
RA Stetter K.O., Short J.M., Noorderwier M.;
RT "The genome of Nanoarchaeum equitans: insights into early archaeal
RT evolution and derived parasitism.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:12984-12988(2003).
CC -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC association with the 30S ribosomal subunit to form the 70S initiation
CC complex. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000305}.
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DR EMBL; AE017199; AAR39359.1; -; Genomic_DNA.
DR AlphaFoldDB; Q74MW8; -.
DR SMR; Q74MW8; -.
DR STRING; 228908.NEQ517; -.
DR EnsemblBacteria; AAR39359; AAR39359; NEQ517.
DR KEGG; neq:NEQ517; -.
DR HOGENOM; CLU_071894_1_0_2; -.
DR Proteomes; UP000000578; Chromosome.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR InterPro; IPR002769; eIF6.
DR PANTHER; PTHR10784; PTHR10784; 1.
DR Pfam; PF01912; eIF-6; 1.
DR SMART; SM00654; eIF6; 1.
PE 3: Inferred from homology;
KW Initiation factor; Protein biosynthesis; Reference proteome.
FT CHAIN 1..208
FT /note="Translation initiation factor 6"
FT /id="PRO_0000153751"
SQ SEQUENCE 208 AA; 22897 MW; D678C75E9CAE4F75 CRC64;
MRVNKIKIYG SDSIGLFGYI ANDIAVLSEV ISKEEEKIIK DTLGLEGIVK TTIAGTPTVG
SFIIGKKDLI IVPSSIYEEE LKKLEELFRV EVVDVVNNAL GNNYYYWPKK NLLFAAEDTK
KEAKLLAKKL NADLYLIDTD IEVGSSLIGN SKMLLHNPDI YIDIEDAKPV TLNMGDKFVG
AAALLNDKGI VVGSKTTGIE LIELQDLF