ID   IF6_SULAC               Reviewed;         223 AA.
AC   P38619; Q4J8U4;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2002, sequence version 2.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=Saci_1465;
OS   Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS   15157 / NCIMB 11770).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=330779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=7711082; DOI=10.1016/0167-4781(95)00024-b;
RA   Moll R., Schmidtke S., Schaefer G.;
RT   "Nucleotide sequence of a gene cluster encoding ribosomal proteins in the
RT   thermoacidophilic crenarchaeon Sulfolobus acidocaldarius.";
RL   Biochim. Biophys. Acta 1261:315-318(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=15995215; DOI=10.1128/jb.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA54640.1; Type=Frameshift; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X77509; CAA54640.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; CP000077; AAY80786.1; -; Genomic_DNA.
DR   PIR; S53700; S53700.
DR   RefSeq; WP_011278288.1; NC_007181.1.
DR   AlphaFoldDB; P38619; -.
DR   SMR; P38619; -.
DR   STRING; 330779.Saci_1465; -.
DR   EnsemblBacteria; AAY80786; AAY80786; Saci_1465.
DR   GeneID; 3474659; -.
DR   KEGG; sai:Saci_1465; -.
DR   PATRIC; fig|330779.12.peg.1409; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   Proteomes; UP000001018; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   CDD; cd00527; IF6; 1.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..223
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_0000153758"
SQ   SEQUENCE   223 AA;  24168 MW;  BC025C9EC7186FE2 CRC64;
     MILDKLSIFG TDNIGIYIFT NDKYTIIPKI DDKEVIEKIQ GILKTEIIQT TISKSVLVGI
     LVTGNNDVIL LPRTALADEI KVIKEQAKDV RVEVVDIRPT ALGNIILSNT HGALIYQDLS
     EAEINKVKKA LQIDTAIKGT IANIITVGSV AVITDKAGLV HIDATEEELK KLSELFKVKL
     DSGTVNFGSV FIRSGLVANR NGVLVGSSTT GAEILRIQRA FSD