IF6_SULIK
ID IF6_SULIK Reviewed; 223 AA.
AC C4KIJ1;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=M164_1802;
OS Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=426118;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M.16.4 / Kamchatka #3;
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC association with the 30S ribosomal subunit to form the 70S initiation
CC complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC Rule:MF_00032}.
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DR EMBL; CP001402; ACR42405.1; -; Genomic_DNA.
DR RefSeq; WP_012711731.1; NC_012726.1.
DR AlphaFoldDB; C4KIJ1; -.
DR SMR; C4KIJ1; -.
DR EnsemblBacteria; ACR42405; ACR42405; M164_1802.
DR GeneID; 7812214; -.
DR GeneID; 7940272; -.
DR KEGG; sid:M164_1802; -.
DR HOGENOM; CLU_071894_1_0_2; -.
DR OMA; GEDTTGP; -.
DR Proteomes; UP000001479; Chromosome.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR HAMAP; MF_00032; eIF_6; 1.
DR InterPro; IPR002769; eIF6.
DR PANTHER; PTHR10784; PTHR10784; 1.
DR Pfam; PF01912; eIF-6; 1.
DR PIRSF; PIRSF006413; IF-6; 1.
DR SMART; SM00654; eIF6; 1.
DR TIGRFAMs; TIGR00323; eIF-6; 1.
PE 3: Inferred from homology;
KW Initiation factor; Protein biosynthesis.
FT CHAIN 1..223
FT /note="Translation initiation factor 6"
FT /id="PRO_1000202008"
SQ SEQUENCE 223 AA; 24473 MW; 84D159EBF0765E5B CRC64;
MNLQRLSIFG TDNIGVYIYT NNKYTVVPRG LDSETKENIV QILGTELIEA EISRSFLLGI
FISGNDNGIL LPKSTIDDEF RFLKENLRDC RVEVLNSKVT ALGNTILTNN KAALIYPEFN
DIEEKIIKET LGVEEIRRGK IAQMITVGSV GVVTNKGGLV HVDTSEKELK ELEKLFGVKI
DIGTVNFGSV FIRSGLVAND KGTLVGASTT GPEILRIQKA LGE