ID   IF6_THEAC               Reviewed;         216 AA.
AC   Q9HM16;
DT   03-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2002, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=Ta0055;
OS   Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC
OS   15155 / AMRC-C165).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273075;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165;
RX   PubMed=11029001; DOI=10.1038/35035069;
RA   Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA   Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT   "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT   acidophilum.";
RL   Nature 407:508-513(2000).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAC11203.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL445063; CAC11203.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_010900483.1; NC_002578.1.
DR   AlphaFoldDB; Q9HM16; -.
DR   SMR; Q9HM16; -.
DR   STRING; 273075.Ta0055m; -.
DR   EnsemblBacteria; CAC11203; CAC11203; CAC11203.
DR   GeneID; 1456963; -.
DR   KEGG; tac:Ta0055; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   OrthoDB; 70525at2157; -.
DR   Proteomes; UP000001024; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   CDD; cd00527; IF6; 1.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..216
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_0000153761"
SQ   SEQUENCE   216 AA;  23505 MW;  605A7971BE5B2357 CRC64;
     MIRKTSVLRS NFIGIYAKAW DDVAFITMMA DEKTVADFQE VLQVDVRRIS IDNSSLIGTM
     MVMNSNGLIV PYGSEITGLG DLDGRNVLQL KDKINAIGND IIANDHGAII HKNFSNRSRK
     EIEDTLGVET IRTTIGNILT VGSAGILTSK GMLVNPETDD DELEFLRDFF KVSVKSGTAN
     FGSIYVGASI VANSKGVLVG KDTTPIEMDR IDDVLS