ID   IF6_THEGJ               Reviewed;         228 AA.
AC   C5A7H2;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032};
DE            Short=aIF-6 {ECO:0000255|HAMAP-Rule:MF_00032};
GN   Name=eif6 {ECO:0000255|HAMAP-Rule:MF_00032}; OrderedLocusNames=TGAM_1682;
OS   Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=593117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15229 / JCM 11827 / EJ3;
RX   PubMed=19558674; DOI=10.1186/gb-2009-10-6-r70;
RA   Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M.,
RA   Anthouard V., Forterre P., Wincker P., Confalonieri F.;
RT   "Genome analysis and genome-wide proteomics of Thermococcus gammatolerans,
RT   the most radioresistant organism known amongst the Archaea.";
RL   Genome Biol. 10:R70.1-R70.23(2007).
CC   -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC       association with the 30S ribosomal subunit to form the 70S initiation
CC       complex. {ECO:0000255|HAMAP-Rule:MF_00032}.
CC   -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00032}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001398; ACS34184.1; -; Genomic_DNA.
DR   RefSeq; WP_015859295.1; NC_012804.1.
DR   AlphaFoldDB; C5A7H2; -.
DR   SMR; C5A7H2; -.
DR   STRING; 593117.TGAM_1682; -.
DR   PaxDb; C5A7H2; -.
DR   EnsemblBacteria; ACS34184; ACS34184; TGAM_1682.
DR   GeneID; 7987592; -.
DR   KEGG; tga:TGAM_1682; -.
DR   PATRIC; fig|593117.10.peg.1688; -.
DR   eggNOG; arCOG04176; Archaea.
DR   HOGENOM; CLU_071894_1_0_2; -.
DR   OMA; GEDTTGP; -.
DR   OrthoDB; 70525at2157; -.
DR   Proteomes; UP000001488; Chromosome.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:InterPro.
DR   CDD; cd00527; IF6; 1.
DR   HAMAP; MF_00032; eIF_6; 1.
DR   InterPro; IPR002769; eIF6.
DR   PANTHER; PTHR10784; PTHR10784; 1.
DR   Pfam; PF01912; eIF-6; 1.
DR   PIRSF; PIRSF006413; IF-6; 1.
DR   SMART; SM00654; eIF6; 1.
DR   TIGRFAMs; TIGR00323; eIF-6; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..228
FT                   /note="Translation initiation factor 6"
FT                   /id="PRO_1000202013"
SQ   SEQUENCE   228 AA;  24907 MW;  49E63D88A43D0D7A CRC64;
     MHIERLDFEN SPYLGVYGFA TDRVAVIREG LGEKKLATLR EVLKVPLIET SVMKSRIVGI
     FVAGNSNALI VPWYIWDAEL DFINAQLREY GIDMEVVPFQ SRLTAFGNLI LANDKGALVS
     KDFTREEARK IEDILGVPVE RGVIADYTAV GSVGVVTNKG GLVHPEATDE ELEWLSDLFK
     VDVYVGTANM GVPFVGSCMI ANSYGVVVGH LTTGPEIVKI EEALGFLG