ID   IFEB_ASCSU              Reviewed;         589 AA.
AC   P23731;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Intermediate filament protein B;
DE            Short=IF-B;
OS   Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6253;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=2583097; DOI=10.1002/j.1460-2075.1989.tb08481.x;
RA   Weber K., Plessmann U., Ulrich W.;
RT   "Cytoplasmic intermediate filament proteins of invertebrates are closer to
RT   nuclear lamins than are vertebrate intermediate filament proteins; sequence
RT   characterization of two muscle proteins of a nematode.";
RL   EMBO J. 8:3221-3227(1989).
CC   -!- SUBUNIT: A and B can form homopolymers.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- TISSUE SPECIFICITY: Giant body muscle cells.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01188}.
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DR   AlphaFoldDB; P23731; -.
DR   SMR; P23731; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005882; C:intermediate filament; IDA:CACAO.
DR   Gene3D; 2.60.40.1260; -; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR016451; Intermed_filament_ifa/ifb.
DR   InterPro; IPR001322; Lamin_tail_dom.
DR   InterPro; IPR036415; Lamin_tail_dom_sf.
DR   Pfam; PF00038; Filament; 1.
DR   Pfam; PF00932; LTD; 1.
DR   PIRSF; PIRSF005546; Intermed_filamnt_Ifb-2; 1.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF74853; SSF74853; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
DR   PROSITE; PS51841; LTD; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Cytoplasm; Direct protein sequencing; Intermediate filament.
FT   CHAIN           1..589
FT                   /note="Intermediate filament protein B"
FT                   /id="PRO_0000063833"
FT   DOMAIN          81..433
FT                   /note="IF rod"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01188"
FT   DOMAIN          466..584
FT                   /note="LTD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01187"
FT   REGION          1..84
FT                   /note="Head"
FT   REGION          85..116
FT                   /note="Coil 1A"
FT   REGION          117..130
FT                   /note="Linker 1"
FT   REGION          131..268
FT                   /note="Coil 1B"
FT   REGION          269..285
FT                   /note="Linker 12"
FT   REGION          286..433
FT                   /note="Coil 2"
FT   REGION          434..589
FT                   /note="Tail"
FT   REGION          446..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   589 AA;  67695 MW;  5EF7D9F6F0AFDED6 CRC64;
     SLKQSQESSE YEIAYRSTIQ PRTAVRTQSR QSGAYSTGAV SGGGGRVLKM VTEMGSASIG
     GISPALSANA AKSFLEATDK EKKEMQGLND RLGNYIDRVK KLEEQNRKLV ADLDELRGRW
     GKDTSEIKIQ YSDSLRDARK EIDDGARRKA EIDVKVARLR DDLAELRNRY EDVQHRRESD
     REKINQWQHA IEDAQSELEM LRARWRQLTE EEKRLNGDNA RIWEELQKAR NDLDEETLGR
     IDFQNQVQTL MEELEFLRRV HEQEVKELQA LLAQAPADTR EFFKNELALA IRDIKDEYDY
     IAKQGKQDME SWYKLKVSEV QGSANRANME SSYQREEVKR MRDNIGDLRG KLGDLEAKNA
     LLEKEVQNLN YQLNDDQRQY EAALNDRDAT LRRMREECQT LVAELQALLD TKQMLDAEIA
     IYRKMLEGEE SRVGLRQMVE QVVKTHSLQQ QEDTDSTRNV RGEVSTKTTF QRSAKGNVTI
     SECDPNGKFI TLENTHRSKD ENLGEHRLKR KLDNRREIVY TIPPNTVLKA GRTMKIYARD
     QGGIHNPPDT LVFDGENTWG IGANVVTSLI NKDGDERATH TQKTIQTGQ