ID   IFE_BRALA               Reviewed;         464 AA.
AC   Q04948;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Non-neuronal cytoplasmic intermediate filament protein;
OS   Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomidae; Branchiostoma.
OX   NCBI_TaxID=7740;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1644059;
RA   Riemer D., Dodemont H., Weber K.;
RT   "Analysis of the cDNA and gene encoding a cytoplasmic intermediate filament
RT   (IF) protein from the cephalochordate Branchiostoma lanceolatum;
RT   implications for the evolution of the IF protein family.";
RL   Eur. J. Cell Biol. 58:128-135(1992).
CC   -!- SUBUNIT: Can form homopolymers.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01188}.
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DR   EMBL; X64522; CAA45827.1; -; mRNA.
DR   PIR; A56600; A56600.
DR   AlphaFoldDB; Q04948; -.
DR   SMR; Q04948; -.
DR   PRIDE; Q04948; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR002957; Keratin_I.
DR   Pfam; PF00038; Filament; 1.
DR   PRINTS; PR01248; TYPE1KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Intermediate filament.
FT   CHAIN           1..464
FT                   /note="Non-neuronal cytoplasmic intermediate filament
FT                   protein"
FT                   /id="PRO_0000063862"
FT   DOMAIN          98..413
FT                   /note="IF rod"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01188"
FT   REGION          1..101
FT                   /note="Head"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          102..133
FT                   /note="Coil 1A"
FT   REGION          134..144
FT                   /note="Linker 1"
FT   REGION          145..237
FT                   /note="Coil 1B"
FT   REGION          238..264
FT                   /note="Linker 2"
FT   REGION          265..413
FT                   /note="Coil 2"
FT   REGION          414..464
FT                   /note="Tail"
FT   REGION          415..464
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..464
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   464 AA;  51300 MW;  095CB4025A761608 CRC64;
     MSTQTKKVTR TIITSSSGGG GGGGGGRASY SSSGRFSGGG GRMRAGGVTS RRSVGSSYSA
     GGGGRVNAVM AAGVMASVGG PAGALQTLSD ARMTRAHEKQ ELSHLNDRFA SYIDKVRYLQ
     ERNSKLEAQI KIQESREAPN IKDLYEKELR DLRALVDELS NDKAQLEIER NNWQEQAEDY
     KMKWQDEAGL RSELEAEIER LKKELDAATM ARLDLENKLS TAQEEIDFLK RVHDEEIRQL
     QDQLNESLTI VEVDSRAAST FAPGPDLTEA LREIRTQYEE LGRVNREDAD VKYKQKFSEL
     AHQRERDNEA LMTARTEVTE LRRNLNSLVA ENEALKSKNH ALEGSLAELE ARMQLEIEEY
     QAAIRDLEQE LETKTSEMAQ QMQAYKMLMD TKMALDMEIA AYRKLLEGEE IRLFGESKEG
     VQQTSSSSSS SYQYSMKSGS GGGGGGSSSG KQQVTVSVSS GEEK