ID   IFI75_MUSCR             Reviewed;         450 AA.
AC   Q921C6; Q91X10;
DT   22-AUG-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Interferon-induced protein 75;
GN   Name=Ifi75;
OS   Mus caroli (Ryukyu mouse) (Ricefield mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10089;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC   TISSUE=Liver;
RX   PubMed=11471051; DOI=10.1007/s00335-001-3015-9;
RA   Weichenhan D., Kunze B., Winking H., Van Geel M., Osoegawa K.,
RA   De Jong P.J., Traut W.;
RT   "Source and component genes of a 6-200 Mb gene cluster in the house
RT   mouse.";
RL   Mamm. Genome 12:590-594(2001).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00185,
CC       ECO:0000255|PROSITE-ProRule:PRU00747}.
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DR   EMBL; AJ401361; CAC47954.1; -; mRNA.
DR   EMBL; AJ401363; CAC47964.1; -; Genomic_DNA.
DR   EMBL; AJ401364; CAC47964.1; JOINED; Genomic_DNA.
DR   EMBL; AJ401365; CAC47964.1; JOINED; Genomic_DNA.
DR   EMBL; AJ401367; CAC47964.1; JOINED; Genomic_DNA.
DR   EMBL; AJ401369; CAC47964.1; JOINED; Genomic_DNA.
DR   EMBL; AJ401371; CAC47964.1; JOINED; Genomic_DNA.
DR   EMBL; AJ401370; CAC47964.1; JOINED; Genomic_DNA.
DR   EMBL; AJ401368; CAC47964.1; JOINED; Genomic_DNA.
DR   EMBL; AJ401366; CAC47964.1; JOINED; Genomic_DNA.
DR   AlphaFoldDB; Q921C6; -.
DR   SMR; Q921C6; -.
DR   MGI; MGI:1890488; Ifi75.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.10.390.10; -; 1.
DR   InterPro; IPR004865; HSR_dom.
DR   InterPro; IPR010919; SAND-like_dom_sf.
DR   InterPro; IPR000770; SAND_dom.
DR   InterPro; IPR043563; Sp110/Sp140/Sp140L.
DR   PANTHER; PTHR46386; PTHR46386; 2.
DR   Pfam; PF03172; HSR; 1.
DR   Pfam; PF01342; SAND; 1.
DR   SMART; SM00258; SAND; 1.
DR   SUPFAM; SSF63763; SSF63763; 1.
DR   PROSITE; PS51414; HSR; 1.
DR   PROSITE; PS50864; SAND; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Phosphoprotein.
FT   CHAIN           1..450
FT                   /note="Interferon-induced protein 75"
FT                   /id="PRO_0000247961"
FT   DOMAIN          1..108
FT                   /note="HSR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00747"
FT   DOMAIN          358..439
FT                   /note="SAND"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00185"
FT   REGION          131..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          170..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          238..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          318..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           251..266
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        195..213
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        245..263
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         175
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BVK9"
FT   MOD_RES         177
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BVK9"
FT   MOD_RES         226
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BVK9"
FT   CONFLICT        30
FT                   /note="S -> P (in Ref. 1; CAC47954)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        36
FT                   /note="T -> A (in Ref. 1; CAC47954)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        261
FT                   /note="G -> R (in Ref. 1; CAC47954)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        354
FT                   /note="G -> E (in Ref. 1; CAC47954)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   450 AA;  50456 MW;  F3EDF70710136A46 CRC64;
     MFTLTKALEK ALLQHFIYMK VNIAYAINKS FPFFETLRDN SFITERMYKE SLEACQNLVP
     LSKVVHNILT SLEQTFQPSV LLTLFSQVNL REYPSLVAIF RSFRNVGYTY EEKNRPPPTL
     LEDLANPAEG CSLQTLLPPP RPQLSLPSHL SSAPRVCDPR ATAQPITEIL DEQPSPSPQA
     VPLPGCIQEG KTIPVSSRDH QRKDKEDSRE MPHSPSGPES VVKDDSPAAN DLEMAQEVLC
     TPANKKARRK KRLNWSNSKR GRQKKKPRQD EMMGVASPGH GVQEKIKAVV SRRTLWKDDS
     STNVKEVTKI LRARMRCAQT SNSQEISKEA SKTSGRKRHG KRTSTAGKTT QVPGKTKNDA
     VDFLSPTFPV TCGKANGTLF QEKLKQGVSK KCIQNEAGDW LTVKEFLNEG RRATSKDWKK
     AIRCNGETLR QLEQKGLLFC TKSKPQKKGA