ID   IFRD1_PIG               Reviewed;         450 AA.
AC   Q5S1U6;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Interferon-related developmental regulator 1;
GN   Name=IFRD1;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Muscle;
RA   Wang T., Xiong Y.Z.;
RT   "Isolation, cloning and characterization of porcine IFRD1.";
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Could play a role in regulating gene activity in the
CC       proliferative and/or differentiative pathways induced by NGF. May be an
CC       autocrine factor that attenuates or amplifies the initial ligand-
CC       induced signal (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PSIP1/LEDGF. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IFRD family. {ECO:0000305}.
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DR   EMBL; AY789133; AAV58829.1; -; mRNA.
DR   RefSeq; NP_001007520.1; NM_001007519.1.
DR   AlphaFoldDB; Q5S1U6; -.
DR   SMR; Q5S1U6; -.
DR   STRING; 9823.ENSSSCP00000017634; -.
DR   PaxDb; Q5S1U6; -.
DR   PRIDE; Q5S1U6; -.
DR   Ensembl; ENSSSCT00015001148; ENSSSCP00015000287; ENSSSCG00015000899.
DR   Ensembl; ENSSSCT00030080629; ENSSSCP00030036963; ENSSSCG00030057691.
DR   Ensembl; ENSSSCT00040054786; ENSSSCP00040022784; ENSSSCG00040039611.
DR   Ensembl; ENSSSCT00060017456; ENSSSCP00060006952; ENSSSCG00060013262.
DR   Ensembl; ENSSSCT00070057725; ENSSSCP00070049072; ENSSSCG00070028773.
DR   GeneID; 493185; -.
DR   KEGG; ssc:493185; -.
DR   CTD; 3475; -.
DR   eggNOG; KOG2842; Eukaryota.
DR   HOGENOM; CLU_031384_1_0_1; -.
DR   InParanoid; Q5S1U6; -.
DR   OrthoDB; 1153292at2759; -.
DR   TreeFam; TF313638; -.
DR   Proteomes; UP000008227; Unplaced.
DR   Proteomes; UP000314985; Chromosome 18.
DR   Genevisible; Q5S1U6; SS.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039777; IFRD.
DR   InterPro; IPR006921; Interferon-rel_develop_reg_C.
DR   InterPro; IPR007701; Interferon-rel_develop_reg_N.
DR   PANTHER; PTHR12354; PTHR12354; 1.
DR   Pfam; PF05004; IFRD; 1.
DR   Pfam; PF04836; IFRD_C; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; Reference proteome.
FT   CHAIN           1..450
FT                   /note="Interferon-related developmental regulator 1"
FT                   /id="PRO_0000153287"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   450 AA;  50123 MW;  F420454DB6EF7219 CRC64;
     MPKNKKRNTP HRGGSGGGGS GAAATTAATA GGQHRNVQPF SDEDASIETM SHCSGYSDPS
     SFAEDGPEVL DEEGTQEDLE YKLKGLIDLT LDKSAKTRQA ALEGIKNALA SRMLYEFILE
     RRMTLTDSIE RCLKKGKSDE QRAAAALASV LCIQLGPGIE SEEVLKTLGP VLKKIICDGT
     ASIQARQTCA TCFGVCCFIA TDDITELYST LQCLENIFTK SYLKEKDSNV ICSTPNTALH
     ISSLLAWTLL LTICPLSEVK KKLEMHVHKL PSLLSSDDVN MRIAAGESLA LLFELARGME
     SDFFYEDMES LTQMLRALAT DGNKHRAKVD KRKQRSVFRD ILRAVEERDF PTETVKFGPE
     RMYIDCWVKK RTYDTFKEIL GSGMQYHLQS NEFLRNVFEL GPPVMLDAAT LKTMKISRFE
     RHLYNSAAFK ARTKARSKCR DKRADVGEFF