IFT20_CAEEL
ID IFT20_CAEEL Reviewed; 129 AA.
AC Q8TA52;
DT 25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Intraflagellar transport protein 20 homolog;
GN Name=ift-20 {ECO:0000312|WormBase:Y110A7A.20};
GN ORFNames=Y110A7A.20 {ECO:0000312|WormBase:Y110A7A.20};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000312|Proteomes:UP000001940};
RN [1] {ECO:0000312|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000312|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2] {ECO:0000305}
RP FUNCTION, IDENTIFICATION IN IFT COMPLEX B, SUBCELLULAR LOCATION, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=28479320; DOI=10.1016/j.cub.2017.04.015;
RA Yi P., Li W.J., Dong M.Q., Ou G.;
RT "Dynein-driven retrograde intraflagellar transport is triphasic in C.
RT elegans sensory cilia.";
RL Curr. Biol. 27:1448-1461(2017).
CC -!- FUNCTION: Component of the intraflagellar transport (IFT) complex B
CC required for transport of proteins in the motile cilium. Required for
CC ciliary entrance and transport of specific ciliary cargo proteins such
CC as che-3 which are related to motility. {ECO:0000269|PubMed:28479320}.
CC -!- SUBUNIT: Component of the IFT complex B composed of at least che-2,
CC che-13, dyf-1, dyf-3, dyf-6, dyf-11, dyf-13, ift-20, ift-74, ift-81,
CC ifta-2, osm-1, osm-5 and osm-6. {ECO:0000269|PubMed:28479320}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000305|PubMed:28479320}.
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DR EMBL; BX284601; CCD66213.1; -; Genomic_DNA.
DR RefSeq; NP_740843.1; NM_170856.1.
DR AlphaFoldDB; Q8TA52; -.
DR SMR; Q8TA52; -.
DR ComplexPortal; CPX-1290; Intraflagellar transport complex B.
DR DIP; DIP-61857N; -.
DR IntAct; Q8TA52; 1.
DR STRING; 6239.Y110A7A.20; -.
DR PaxDb; Q8TA52; -.
DR EnsemblMetazoa; Y110A7A.20.1; Y110A7A.20.1; WBGene00022465.
DR GeneID; 260266; -.
DR KEGG; cel:CELE_Y110A7A.20; -.
DR UCSC; Y110A7A.20; c. elegans.
DR CTD; 260266; -.
DR WormBase; Y110A7A.20; CE23246; WBGene00022465; ift-20.
DR eggNOG; ENOG502RYYR; Eukaryota.
DR GeneTree; ENSGT00390000003413; -.
DR HOGENOM; CLU_134163_2_0_1; -.
DR InParanoid; Q8TA52; -.
DR OMA; CIQMMTE; -.
DR OrthoDB; 1589590at2759; -.
DR PhylomeDB; Q8TA52; -.
DR Reactome; R-CEL-5620924; Intraflagellar transport.
DR PRO; PR:Q8TA52; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00022465; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR GO; GO:0005929; C:cilium; IBA:GO_Central.
DR GO; GO:0030425; C:dendrite; IDA:WormBase.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0030992; C:intraciliary transport particle B; IBA:GO_Central.
DR GO; GO:0043025; C:neuronal cell body; IDA:WormBase.
DR GO; GO:0097730; C:non-motile cilium; IDA:WormBase.
DR GO; GO:0051642; P:centrosome localization; IBA:GO_Central.
DR GO; GO:0042073; P:intraciliary transport; IBA:GO_Central.
DR GO; GO:0061512; P:protein localization to cilium; IBA:GO_Central.
DR InterPro; IPR028172; FT20.
DR PANTHER; PTHR31978; PTHR31978; 1.
DR Pfam; PF14931; IFT20; 1.
PE 1: Evidence at protein level;
KW Cell projection; Cilium; Coiled coil; Reference proteome.
FT CHAIN 1..129
FT /note="Intraflagellar transport protein 20 homolog"
FT /evidence="ECO:0000305"
FT /id="PRO_0000442220"
FT COILED 89..121
FT /evidence="ECO:0000255"
SQ SEQUENCE 129 AA; 14930 MW; C6C2BFA8CF17E950 CRC64;
MGDEQLAKAG LFVDDFNRLR LIDPDVAELL QSAQDKSSEF NDQLKNFQTT TGGLIDSIEE
FANVVETEKI RAMMVRNTQE RDLAEDDPVL LQMTIRELTV EKERLRVELE AVRKIEKEQD
ECIQMMTEH