ID   IFT46_SCHJA             Reviewed;         330 AA.
AC   Q5DHJ5;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Intraflagellar transport protein 46 homolog;
GN   ORFNames=SJCHGC08984;
OS   Schistosoma japonicum (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6182;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16617374; DOI=10.1371/journal.ppat.0020029;
RA   Liu F., Lu J., Hu W., Wang S.-Y., Cui S.-J., Chi M., Yan Q., Wang X.-R.,
RA   Song H.-D., Xu X.-N., Wang J.-J., Zhang X.-L., Zhang X., Wang Z.-Q.,
RA   Xue C.-L., Brindley P.J., McManus D.P., Yang P.-Y., Feng Z., Chen Z.,
RA   Han Z.-G.;
RT   "New perspectives on host-parasite interplay by comparative transcriptomic
RT   and proteomic analyses of Schistosoma japonicum.";
RL   PLoS Pathog. 2:268-281(2006).
CC   -!- FUNCTION: Forms part of a complex involved in intraflagellar transport
CC       (IFT), the bi-directional movement of particles required for the
CC       assembly, maintenance and functioning of primary cilia. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC       {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Note=Expression
CC       is concentrated at the cilium basal body but is also detected along the
CC       length of the cilium. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IFT46 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY812979; AAW24711.1; -; mRNA.
DR   AlphaFoldDB; Q5DHJ5; -.
DR   SMR; Q5DHJ5; -.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0042073; P:intraciliary transport; IEA:InterPro.
DR   InterPro; IPR022088; Intraflagellar_transp_cmplxB.
DR   PANTHER; PTHR13376; PTHR13376; 1.
DR   Pfam; PF12317; IFT46_B_C; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Cytoplasm; Cytoskeleton.
FT   CHAIN           1..330
FT                   /note="Intraflagellar transport protein 46 homolog"
FT                   /id="PRO_0000085519"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          55..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..103
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   330 AA;  37632 MW;  7B72B274C3C8418E CRC64;
     MDRPYDETVD IPDSEDIATP RLQQSLAENL DKLRDSYGDN SKLLTKTNSE LANRSIKTAS
     KSVIRMDSSS EKLCDRGSSD DDDDDDNDDD EDEDDDDDDE NANIHDATEG VYNPADYEHL
     TVSSEIKEIF EYIQRYTPQT IELETKLKPF IPDYIPAVGD IDAFLKVPRP DGKPDYLGLL
     VLDEPCANQS DPTVLDLQLR ALSKQTTTKQ VTVKSLENAE HQTKAIENWI KSIADLYRTK
     PPPTVHYTKN MPEISQLMSE WPKSFEESIS NMQLSLSQLD CSLKDYVDII CALLDIPVYN
     NRIHSLHLLF SLYLEFKNSQ HFRQNESVIT