IFTAP_BOVIN
ID IFTAP_BOVIN Reviewed; 242 AA.
AC Q3ZBP0;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Intraflagellar transport-associated protein;
DE AltName: Full=Protein HEPIS;
GN Name=IFTAP;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Heart ventricle;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Seems to play a role in ciliary BBSome localization, maybe
CC through interaction with IFT-A complex. {ECO:0000250|UniProtKB:Q86VG3}.
CC -!- SUBUNIT: Interacts with IFT122; the interaction associates IFTAP with
CC IFT-A complex. {ECO:0000250|UniProtKB:Q86VG3}.
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DR EMBL; BC103191; AAI03192.1; -; mRNA.
DR RefSeq; NP_001029922.1; NM_001034750.2.
DR RefSeq; XP_005216445.1; XM_005216388.3.
DR AlphaFoldDB; Q3ZBP0; -.
DR STRING; 9913.ENSBTAP00000028797; -.
DR PaxDb; Q3ZBP0; -.
DR Ensembl; ENSBTAT00000028797; ENSBTAP00000028797; ENSBTAG00000021611.
DR Ensembl; ENSBTAT00000079262; ENSBTAP00000067726; ENSBTAG00000021611.
DR Ensembl; ENSBTAT00000079860; ENSBTAP00000060968; ENSBTAG00000021611.
DR GeneID; 614192; -.
DR KEGG; bta:614192; -.
DR CTD; 119710; -.
DR VEuPathDB; HostDB:ENSBTAG00000021611; -.
DR VGNC; VGNC:52633; IFTAP.
DR eggNOG; ENOG502S1X7; Eukaryota.
DR GeneTree; ENSGT00390000013149; -.
DR HOGENOM; CLU_077972_0_0_1; -.
DR InParanoid; Q3ZBP0; -.
DR OMA; FTHKNEP; -.
DR TreeFam; TF335968; -.
DR Proteomes; UP000009136; Chromosome 15.
DR Bgee; ENSBTAG00000021611; Expressed in oocyte and 106 other tissues.
DR ExpressionAtlas; Q3ZBP0; baseline and differential.
DR GO; GO:0097731; C:9+0 non-motile cilium; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0120160; F:intraciliary transport particle A binding; ISS:UniProtKB.
DR GO; GO:0007340; P:acrosome reaction; IBA:GO_Central.
DR GO; GO:0007283; P:spermatogenesis; IBA:GO_Central.
DR InterPro; IPR040028; IFTAP.
DR PANTHER; PTHR35543; PTHR35543; 1.
DR Pfam; PF17722; IFTAP; 1.
PE 2: Evidence at transcript level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..242
FT /note="Intraflagellar transport-associated protein"
FT /id="PRO_0000288853"
FT MOD_RES 57
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q86VG3"
SQ SEQUENCE 242 AA; 27213 MW; ECCD4AC769328431 CRC64;
MPAKTPELEM MDEDRLIEEV LDKFVNCHEQ TYEEFLRTFT HLSKDNVTKR EAFGTNSSEN
NFTSIKFTQR NEPNDCRLSN KAIFLHTSSQ CSEEEQIMIG DGQKAGSSFQ GDLNRAGKVK
VDNFLDIEDL DLDEEINPQL SKDVLLLPGQ VEQEVSLSVP SYIPSVAIQP VTPGTKPRPT
VKAADKQSKE IVGDEVQPFS LDEEFDYDAV VLTPKFTPAE MNAIKELSKQ KTKSADLEDP
HD