IGAA_YERPE
ID IGAA_YERPE Reviewed; 715 AA.
AC P58722; Q0WKG0;
DT 31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT 31-JAN-2002, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Putative membrane protein IgaA homolog;
GN OrderedLocusNames=YPO0142, y3922, YP_0143;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IgaA family. {ECO:0000305}.
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DR EMBL; AL590842; CAL18828.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM87466.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS60421.1; -; Genomic_DNA.
DR PIR; AC0018; AC0018.
DR RefSeq; WP_002208908.1; NZ_WUCM01000004.1.
DR RefSeq; YP_002345228.1; NC_003143.1.
DR AlphaFoldDB; P58722; -.
DR SMR; P58722; -.
DR IntAct; P58722; 1.
DR STRING; 214092.YPO0142; -.
DR PaxDb; P58722; -.
DR DNASU; 1148869; -.
DR EnsemblBacteria; AAM87466; AAM87466; y3922.
DR EnsemblBacteria; AAS60421; AAS60421; YP_0143.
DR GeneID; 57974458; -.
DR KEGG; ype:YPO0142; -.
DR KEGG; ypk:y3922; -.
DR KEGG; ypm:YP_0143; -.
DR PATRIC; fig|214092.21.peg.370; -.
DR eggNOG; ENOG502Z8KK; Bacteria.
DR HOGENOM; CLU_014723_0_0_6; -.
DR OMA; DLIYPPH; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR010771; IgaA.
DR Pfam; PF07095; IgaA; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..715
FT /note="Putative membrane protein IgaA homolog"
FT /id="PRO_0000215018"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 235..255
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 663..683
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 715 AA; 80006 MW; 5A2CB380FD1049F4 CRC64;
MSTIVLILAL LLTSLIAVGL LWWLRFRRPH PITAALPFVK LTHRKLTPEE RVSIENYLRN
QQNKHGFNTQ PAFDSHALAA STSSTPMLVL TPQSDNVYSV TRAITRYGVA SDEPNKWRYY
LDSIEVHLPS AWEQYITQDN DVELIQTQTI PLVISLNGHT LNNHQSENTY QPILPSVSKN
ASIRKEDSEH IELLNIRKET PEEYALHGPN GLKEACAICI ALLLLFFALS GPTVTLPWLV
IVAVSLTCWA CWYLFRPLSE KDLREVHCLN GTPKRWGLFG ESNQGQINNI SLGIVDLIYP
AHWGPYFVHD LGKKTHIDIY LNRQVVRQGA FLSLHDEMKM FPLQRWGKNL TLIVGSLLVL
VLLLIYVPLG LPLKLSVAWL QGAQSQQVTS VAALDKMPLR IGDMLKAQGN GMCYVPPNIQ
NTRGFVFTPF DCSGIYWNTA SPLPQPESET IEKAAALVET INKQLHPQGS DASVNPKLAT
AIEKSGMILL DDFSDIVLKT QALCSENTDC IRLKNALVNL GNAKNWSALV KRAQSGNLEG
MNVLLRPISA DVLENLINTA ASSFVYRETH LATEALNSPP PGGFLITSDE GKQLVNHPAP
TLPLFDYSAL EQWRELQRLS ALLLDTPFKA EGIITNITTD ANGTRHIALH SEPDIVTLGR
YLATSLLLLV LIFCLVVNMV LLIQRAMKNR RRMDNIQRYY DDCFNQTLTP PPFLR