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IGAA_YERPE
ID   IGAA_YERPE              Reviewed;         715 AA.
AC   P58722; Q0WKG0;
DT   31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   31-JAN-2002, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Putative membrane protein IgaA homolog;
GN   OrderedLocusNames=YPO0142, y3922, YP_0143;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IgaA family. {ECO:0000305}.
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DR   EMBL; AL590842; CAL18828.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM87466.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS60421.1; -; Genomic_DNA.
DR   PIR; AC0018; AC0018.
DR   RefSeq; WP_002208908.1; NZ_WUCM01000004.1.
DR   RefSeq; YP_002345228.1; NC_003143.1.
DR   AlphaFoldDB; P58722; -.
DR   SMR; P58722; -.
DR   IntAct; P58722; 1.
DR   STRING; 214092.YPO0142; -.
DR   PaxDb; P58722; -.
DR   DNASU; 1148869; -.
DR   EnsemblBacteria; AAM87466; AAM87466; y3922.
DR   EnsemblBacteria; AAS60421; AAS60421; YP_0143.
DR   GeneID; 57974458; -.
DR   KEGG; ype:YPO0142; -.
DR   KEGG; ypk:y3922; -.
DR   KEGG; ypm:YP_0143; -.
DR   PATRIC; fig|214092.21.peg.370; -.
DR   eggNOG; ENOG502Z8KK; Bacteria.
DR   HOGENOM; CLU_014723_0_0_6; -.
DR   OMA; DLIYPPH; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010771; IgaA.
DR   Pfam; PF07095; IgaA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..715
FT                   /note="Putative membrane protein IgaA homolog"
FT                   /id="PRO_0000215018"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        663..683
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   715 AA;  80006 MW;  5A2CB380FD1049F4 CRC64;
     MSTIVLILAL LLTSLIAVGL LWWLRFRRPH PITAALPFVK LTHRKLTPEE RVSIENYLRN
     QQNKHGFNTQ PAFDSHALAA STSSTPMLVL TPQSDNVYSV TRAITRYGVA SDEPNKWRYY
     LDSIEVHLPS AWEQYITQDN DVELIQTQTI PLVISLNGHT LNNHQSENTY QPILPSVSKN
     ASIRKEDSEH IELLNIRKET PEEYALHGPN GLKEACAICI ALLLLFFALS GPTVTLPWLV
     IVAVSLTCWA CWYLFRPLSE KDLREVHCLN GTPKRWGLFG ESNQGQINNI SLGIVDLIYP
     AHWGPYFVHD LGKKTHIDIY LNRQVVRQGA FLSLHDEMKM FPLQRWGKNL TLIVGSLLVL
     VLLLIYVPLG LPLKLSVAWL QGAQSQQVTS VAALDKMPLR IGDMLKAQGN GMCYVPPNIQ
     NTRGFVFTPF DCSGIYWNTA SPLPQPESET IEKAAALVET INKQLHPQGS DASVNPKLAT
     AIEKSGMILL DDFSDIVLKT QALCSENTDC IRLKNALVNL GNAKNWSALV KRAQSGNLEG
     MNVLLRPISA DVLENLINTA ASSFVYRETH LATEALNSPP PGGFLITSDE GKQLVNHPAP
     TLPLFDYSAL EQWRELQRLS ALLLDTPFKA EGIITNITTD ANGTRHIALH SEPDIVTLGR
     YLATSLLLLV LIFCLVVNMV LLIQRAMKNR RRMDNIQRYY DDCFNQTLTP PPFLR
 
 
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