ID   IGEB_MOUSE              Reviewed;         557 AA.
AC   P03975;
DT   23-OCT-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-1986, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=IgE-binding protein;
GN   Name=Iap;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3873067; DOI=10.1073/pnas.82.8.2460;
RA   Martens C.L., Huff T.F., Jardieu P., Trounstine M.L., Coffman R.L.,
RA   Ishizaka K., Moore K.W.;
RT   "cDNA clones encoding IgE-binding factors from a rat-mouse T-cell
RT   hybridoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:2460-2464(1985).
CC   -!- MISCELLANEOUS: This hybridoma was generated by fusion of rat
CC       lymphocytes with cells of the AKR mouse thyoma BW5147.
CC   -!- MISCELLANEOUS: This sequence binds only rat IgE.
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DR   EMBL; M10062; AAA37291.1; -; mRNA.
DR   PIR; A01858; EBRTMS.
DR   AlphaFoldDB; P03975; -.
DR   SMR; P03975; -.
DR   SwissPalm; P03975; -.
DR   EPD; P03975; -.
DR   MaxQB; P03975; -.
DR   PeptideAtlas; P03975; -.
DR   PRIDE; P03975; -.
DR   ProteomicsDB; 267219; -.
DR   MGI; MGI:96306; Iap.
DR   OrthoDB; 754103at2759; -.
DR   PRO; PR:P03975; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P03975; protein.
DR   GO; GO:0019863; F:IgE binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
DR   Gene3D; 1.10.375.10; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR045345; Gag_p24_C.
DR   InterPro; IPR000721; Gag_p24_N.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR008919; Retrov_capsid_N.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF00607; Gag_p24; 1.
DR   Pfam; PF19317; Gag_p24_C; 1.
DR   Pfam; PF00665; rve; 1.
DR   SUPFAM; SSF47943; SSF47943; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   2: Evidence at transcript level;
KW   Hybridoma; IgE-binding protein; Reference proteome.
FT   CHAIN           1..557
FT                   /note="IgE-binding protein"
FT                   /id="PRO_0000084173"
FT   DOMAIN          344..534
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
FT   REGION          113..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   557 AA;  62747 MW;  C53C479890B7FD82 CRC64;
     MALQVMFGLE FFLVLEALLF LFTCYQVVKA GRILDEIQDK LSEVKRGERV GTKRKYGTQN
     KYTGLSKGLE PEEKLRLGRN TWREIRRKRG KREKKKDQLA EVSRKRSLCS SLDGLGKPAL
     SSSEAGEESS SEETDWEEEA AHYQPANWSR KKPKAAGEGQ FADWPQGSRL QGPPYAESPP
     CVVRQQCAER CAERQCAERQ CADSFIPREE QRKIQQAFPV FEGAEGGRVH APVEYLQIKE
     IAESVRKYGT NANFTLVQLD RLAGMALTPA DWQTVVKAAL PSMGKYMEWR ALWHEAAQAQ
     ARANAAALTP EQRDWTFDLL TGQGAYSADQ TNYHWGAYAQ ISSTAIRPGR RSRAGETTGQ
     LTKIIQGPQE SFSDFVARMT EAAERIFGES EQAAPLIEQL IYEQATKECR AVHSPKKEQR
     LTRLAQGLSR AWGKPRLLKT DNGPAYTSQK FQQFCRQMDV THLTGLPYNP QGQGIVERAH
     RTLKAYLIKQ KRGTFEETVP RAPRVSVSLA LFTLNFLNID AHGHTAAERH VQSQIGPMRW
     LNGKMSLIIN GMARILS