ID   IGHM_CANLF              Reviewed;         450 AA.
AC   P01874;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Ig mu chain C region;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   PROTEIN SEQUENCE OF 1-177 (MOO).
RX   PubMed=117299; DOI=10.1016/0161-5890(79)90119-6;
RA   McCumber L.J., Capra J.D.;
RT   "The complete amino-acid sequence of a canine mu chain.";
RL   Mol. Immunol. 16:565-570(1979).
RN   [2]
RP   PROTEIN SEQUENCE OF 178-450 (MOO).
RX   PubMed=653360; DOI=10.1126/science.653360;
RA   Wasserman R.L., Capra J.D.;
RT   "Amino acid sequence of the Fc region of a canine immunoglobulin M:
RT   interspecies homology for the IgM class.";
RL   Science 200:1159-1161(1978).
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DR   PIR; A93131; MHDG.
DR   Proteomes; UP000002254; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0050776; P:regulation of immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 4.
DR   SMART; SM00407; IGc1; 4.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 4.
DR   PROSITE; PS00290; IG_MHC; 3.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Immunoglobulin domain; Reference proteome.
FT   CHAIN           <1..450
FT                   /note="Ig mu chain C region"
FT                   /id="PRO_0000153617"
FT   NON_TER         1
SQ   SEQUENCE   450 AA;  48896 MW;  9D460DA9D1012F5D CRC64;
     GSASAPSIFP LVSCENSNPT STVAMGCLAR DFLPGSITFS WKYEBLSAIN STRGFPSVLR
     GGKYVATSQV FLPSVDIIQG TDEHIVCKVR HSBGBKQKBV PLPVMLTLPP EVSGFIPPRD
     AFFGBPRKSQ LICQASGFSP RQVWSLRDGK QIESGVTTNE VZAZAKZSGP TTYKVTSMLT
     IQEDAWLSQS VFTCKVEHRG LTFQQNASSM CTSDQPVGIS IFTIPPSFAS IFNTKSAKLS
     CLVTDLATYD SVTISWTREE NGALKTHTNI SESHPNGTFS AMGEATVCVE EWESGEQFTC
     TVTHTDLPSV LKQTISRPKG VAVHMPSVYV LPPSREQLDL RESATLSCLV TGYSPPDVFV
     QWVQKGQPVP PDSYVTSAPM PEPQAPGLYF AHSILTVSEE EWNAGETYTC VVAHESLPNR
     VTERSVDKST GKPTLYNVSL VLSDTAGZCY