ID   IGRA_PSES2              Reviewed;         351 AA.
AC   P18896;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Increased glyphosate resistance protein;
GN   Name=igrA {ECO:0000303|PubMed:2268152};
OS   Pseudomonas sp. (strain PG2982).
OC   Bacteria; Proteobacteria.
OX   NCBI_TaxID=308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND HERBICIDE RESISTANCE.
RX   PubMed=2268152; DOI=10.1128/aem.56.11.3382-3388.1990;
RA   Fitzgibbon J.E., Braymer H.D.;
RT   "Cloning of a gene from Pseudomonas sp. strain PG2982 conferring increased
RT   glyphosate resistance.";
RL   Appl. Environ. Microbiol. 56:3382-3388(1990).
CC   -!- FUNCTION: Confers an increase in glyphosate resistance when expressed
CC       in E.coli. {ECO:0000269|PubMed:2268152}.
CC   -!- MISCELLANEOUS: PG2982 is able to utilize glyphosate and other
CC       phosphonate compounds as a sole phosphorus source; it can grow in over
CC       100 mM glyphosate. {ECO:0000269|PubMed:2268152}.
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DR   EMBL; M37389; AAA25856.1; -; Genomic_DNA.
DR   PIR; A43793; A43793.
DR   AlphaFoldDB; P18896; -.
DR   GO; GO:0009635; P:response to herbicide; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Herbicide resistance.
FT   CHAIN           1..351
FT                   /note="Increased glyphosate resistance protein"
FT                   /id="PRO_0000084176"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   351 AA;  39459 MW;  43EB6A366E7E473B CRC64;
     MHREDDSTST GRREERLSTG KGDSLQPGPD QRIFQTALYR PQRHGLILFP QRLYGNCLAP
     LAYSNYVAPR ELHSSIHAEG RTLSVRLIML FVNTSKRSRT LPPVGSTVMR ILVNLCQLLS
     AEFQLLQGSQ RLIFKLCYRT CPDQRRGDTR VAQCPGDSHL SQCLTATFRN GVQRPDAPQQ
     LFVLCTGLQG AALIRPRPFG DSVQIAGGQQ SLSQRRKDNA AGSDLAKGIE QAIFDPAIEH
     VVIGLMNEKR NPLFLQDRGS LLRQFRRIAG NPHIKRLALT VQMRERSHRL FQRRGGVHTV
     RIEDVDIVEP HPLQRPGRGW RSGICDLPPM PPYGPGHMSQ PAFEEMIISS R