ID   IGW1_GINCI              Reviewed;          53 AA.
AC   P83981; P83982; P83983;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=IgW transmembrane form Tm1T3/Tm6T3/Tm3C4;
DE   Flags: Fragment;
OS   Ginglymostoma cirratum (Nurse shark) (Squalus cirratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes;
OC   Ginglymostomatidae; Ginglymostoma.
OX   NCBI_TaxID=7801;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE, AND TISSUE SPECIFICITY.
RC   TISSUE=Spleen {ECO:0000269|PubMed:15240702};
RX   PubMed=15240702; DOI=10.4049/jimmunol.173.2.1129;
RA   Rumfelt L.L., Diaz M., Lohr R.L., Mochon E., Flajnik M.F.;
RT   "Unprecedented multiplicity of Ig transmembrane and secretory mRNA forms in
RT   the cartilaginous fish.";
RL   J. Immunol. 173:1129-1139(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in the spleen, pancreas, peripheral blood
CC       lymphocytes and at low levels in the epigonal organ.
CC       {ECO:0000269|PubMed:15240702}.
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DR   AlphaFoldDB; P83981; -.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Adaptive immunity; Immunity; Immunoglobulin; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           <1..53
FT                   /note="IgW transmembrane form Tm1T3/Tm6T3/Tm3C4"
FT                   /id="PRO_0000059860"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000303|PubMed:15240702"
SQ   SEQUENCE   53 AA;  5758 MW;  3DB61AA20F2E6C72 CRC64;
     VQAVPPDVKG EEGKEEVEDM DGDDNAPTVA AFAILFILSF LYSTFVTVVK VQQ