ID   IGW1_HETFR              Reviewed;         144 AA.
AC   P83742; P83744;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=IgW chain C region, secreted form 1/3;
DE   Flags: Fragment;
OS   Heterodontus francisci (Horn shark) (Cestracion francisci).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Heterodontoidea; Heterodontiformes;
OC   Heterodontidae; Heterodontus.
OX   NCBI_TaxID=7792;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Epigonal organ {ECO:0000269|PubMed:15240702};
RX   PubMed=15240702; DOI=10.4049/jimmunol.173.2.1129;
RA   Rumfelt L.L., Diaz M., Lohr R.L., Mochon E., Flajnik M.F.;
RT   "Unprecedented multiplicity of Ig transmembrane and secretory mRNA forms in
RT   the cartilaginous fish.";
RL   J. Immunol. 173:1129-1139(2004).
RN   [2] {ECO:0000305}
RP   TISSUE SPECIFICITY.
RA   Rumfelt L.L., Diaz M., Lohr R.L., Mochon E., Flajnik M.F.;
RL   Submitted (JAN-2004) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000303|PubMed:15240702}.
CC   -!- TISSUE SPECIFICITY: Expressed mainly in lymphoid tissues including
CC       spleen, epigonal organ and circulating lymphocytes.
CC       {ECO:0000269|Ref.2}.
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DR   AlphaFoldDB; P83742; -.
DR   SMR; P83742; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   2: Evidence at transcript level;
KW   Adaptive immunity; Disulfide bond; Glycoprotein; Immunity; Immunoglobulin;
KW   Secreted.
FT   CHAIN           <1..144
FT                   /note="IgW chain C region, secreted form 1/3"
FT                   /id="PRO_0000059863"
FT   DOMAIN          <1..82
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000255"
FT   REGION          87..144
FT                   /note="Secretory tail"
FT   CARBOHYD        3
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        43
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        123
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        11..68
FT                   /evidence="ECO:0000250|UniProtKB:P01842,
FT                   ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         1
FT                   /evidence="ECO:0000303|PubMed:15240702"
SQ   SEQUENCE   144 AA;  15848 MW;  A25661E0DC7EE1FC CRC64;
     VYNQTTAVLG CVISGFYPDS VQVSWKKDRV DQSGVVLHSK QRNDSTFETV SYLTVPVVEW
     TTGDVYTCEV SHAGSRFNDR ISMRYQKGGT INLPVPGGNT PCTCPPCSCS GCMPKLVYQT
     DLNVTLENGG QLQYNCHQQA CKIK