ID   IGW4_HETFR              Reviewed;          49 AA.
AC   P83978; P83979; P83980;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=IgW transmembrane form Tm2T7/Tm7T7/Tm3T3;
DE   Flags: Fragment;
OS   Heterodontus francisci (Horn shark) (Cestracion francisci).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Heterodontoidea; Heterodontiformes;
OC   Heterodontidae; Heterodontus.
OX   NCBI_TaxID=7792;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Spleen {ECO:0000269|PubMed:15240702};
RX   PubMed=15240702; DOI=10.4049/jimmunol.173.2.1129;
RA   Rumfelt L.L., Diaz M., Lohr R.L., Mochon E., Flajnik M.F.;
RT   "Unprecedented multiplicity of Ig transmembrane and secretory mRNA forms in
RT   the cartilaginous fish.";
RL   J. Immunol. 173:1129-1139(2004).
RN   [2] {ECO:0000305}
RP   TISSUE SPECIFICITY.
RA   Rumfelt L.L., Diaz M., Lohr R.L., Mochon E., Flajnik M.F.;
RL   Submitted (JAN-2004) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in the spleen. May also be expressed in
CC       other lymphoid tissues. {ECO:0000269|Ref.2}.
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DR   AlphaFoldDB; P83978; -.
DR   SMR; P83978; -.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Adaptive immunity; Glycoprotein; Immunity; Immunoglobulin; Membrane;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           <1..49
FT                   /note="IgW transmembrane form Tm2T7/Tm7T7/Tm3T3"
FT                   /id="PRO_0000059866"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
FT                   /evidence="ECO:0000303|PubMed:15240702"
SQ   SEQUENCE   49 AA;  5424 MW;  267B9895FDC6E193 CRC64;
     EDNLSDLEGK EEAGDWDGDD NVLTVAAFAI LFILSFLYST FVTVVKVQQ