IHFA_BRASB
ID IHFA_BRASB Reviewed; 119 AA.
AC A5EKG4;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Integration host factor subunit alpha {ECO:0000255|HAMAP-Rule:MF_00380};
DE Short=IHF-alpha {ECO:0000255|HAMAP-Rule:MF_00380};
GN Name=ihfA {ECO:0000255|HAMAP-Rule:MF_00380};
GN Synonyms=himA {ECO:0000255|HAMAP-Rule:MF_00380};
GN OrderedLocusNames=BBta_4630;
OS Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Bradyrhizobium; unclassified Bradyrhizobium.
OX NCBI_TaxID=288000;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTAi1 / ATCC BAA-1182;
RX PubMed=17540897; DOI=10.1126/science.1139548;
RA Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C.,
RA Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E.,
RA Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL Science 316:1307-1312(2007).
CC -!- FUNCTION: This protein is one of the two subunits of integration host
CC factor, a specific DNA-binding protein that functions in genetic
CC recombination as well as in transcriptional and translational control.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000255|HAMAP-
CC Rule:MF_00380}.
CC -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
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DR EMBL; CP000494; ABQ36658.1; -; Genomic_DNA.
DR RefSeq; WP_012044648.1; NC_009485.1.
DR AlphaFoldDB; A5EKG4; -.
DR SMR; A5EKG4; -.
DR STRING; 288000.BBta_4630; -.
DR EnsemblBacteria; ABQ36658; ABQ36658; BBta_4630.
DR KEGG; bbt:BBta_4630; -.
DR eggNOG; COG0776; Bacteria.
DR HOGENOM; CLU_105066_1_1_5; -.
DR OMA; IYVRGFG; -.
DR OrthoDB; 1847472at2; -.
DR Proteomes; UP000000246; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR CDD; cd13835; IHF_A; 1.
DR Gene3D; 4.10.520.10; -; 1.
DR HAMAP; MF_00380; IHF_alpha; 1.
DR InterPro; IPR000119; Hist_DNA-bd.
DR InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR InterPro; IPR005684; IHF_alpha.
DR PANTHER; PTHR33175; PTHR33175; 1.
DR Pfam; PF00216; Bac_DNA_binding; 1.
DR PRINTS; PR01727; DNABINDINGHU.
DR SMART; SM00411; BHL; 1.
DR SUPFAM; SSF47729; SSF47729; 1.
DR TIGRFAMs; TIGR00987; himA; 1.
DR PROSITE; PS00045; HISTONE_LIKE; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW Translation regulation.
FT CHAIN 1..119
FT /note="Integration host factor subunit alpha"
FT /id="PRO_1000060536"
FT REGION 96..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 119 AA; 13042 MW; 86C5BC112497A583 CRC64;
MTGTGKTVTR VDLCEAVYQK VGLSRTESSA FVELVLKEIT DCLERGETVK LSSFGSFMVR
KKGQRIGRNP KTGTEVPISP RRVMVFKPSA ILKQRINGQQ GSGKMNGEAS HEQLSAEPE