ID   IHFA_BRUSU              Reviewed;         107 AA.
AC   P64391; G0K8S6; Q8YGI0;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Integration host factor subunit alpha;
DE            Short=IHF-alpha;
GN   Name=ihfA; Synonyms=himA; OrderedLocusNames=BR0778, BS1330_I0774;
OS   Brucella suis biovar 1 (strain 1330).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=204722;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=12271122; DOI=10.1073/pnas.192319099;
RA   Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA   Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA   Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA   Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA   Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA   Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT   "The Brucella suis genome reveals fundamental similarities between animal
RT   and plant pathogens and symbionts.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=22038969; DOI=10.1128/jb.06181-11;
RA   Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT   "Revised genome sequence of Brucella suis 1330.";
RL   J. Bacteriol. 193:6410-6410(2011).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE014291; AAN29707.1; -; Genomic_DNA.
DR   EMBL; CP002997; AEM18124.1; -; Genomic_DNA.
DR   RefSeq; WP_002963914.1; NZ_KN046804.1.
DR   AlphaFoldDB; P64391; -.
DR   SMR; P64391; -.
DR   EnsemblBacteria; AEM18124; AEM18124; BS1330_I0774.
DR   GeneID; 45124214; -.
DR   GeneID; 55590491; -.
DR   KEGG; bms:BR0778; -.
DR   KEGG; bsi:BS1330_I0774; -.
DR   PATRIC; fig|204722.21.peg.2655; -.
DR   HOGENOM; CLU_105066_1_1_5; -.
DR   OMA; IYVRGFG; -.
DR   PhylomeDB; P64391; -.
DR   Proteomes; UP000007104; Chromosome I.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..107
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000105002"
SQ   SEQUENCE   107 AA;  11972 MW;  598C359521253417 CRC64;
     MGGKTVTRAD LAEAVYRKVG LSRTESAALV EMILDEVCDA IVNGETVKLS SFATFQVRDK
     NERIGRNPKT GEEVPILPRR VMTFKASNVL KQRILQEHQK RQGKTSK