ID   IHFA_BUCAI              Reviewed;         102 AA.
AC   P57231;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Integration host factor subunit alpha;
DE            Short=IHF-alpha;
GN   Name=ihfA; Synonyms=himA; OrderedLocusNames=BU131;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; BA000003; BAB12849.1; -; Genomic_DNA.
DR   RefSeq; NP_239963.1; NC_002528.1.
DR   RefSeq; WP_009874087.1; NC_002528.1.
DR   AlphaFoldDB; P57231; -.
DR   SMR; P57231; -.
DR   STRING; 107806.10038814; -.
DR   EnsemblBacteria; BAB12849; BAB12849; BAB12849.
DR   KEGG; buc:BU131; -.
DR   PATRIC; fig|107806.10.peg.140; -.
DR   eggNOG; COG0776; Bacteria.
DR   HOGENOM; CLU_105066_1_3_6; -.
DR   OMA; IYVRGFG; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation; Translation regulation.
FT   CHAIN           1..102
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000105003"
SQ   SEQUENCE   102 AA;  11840 MW;  C48354AD4FC6EE25 CRC64;
     MVLTKAAISE NLFEKLQLTK KESKEFVEFF FEEVRKSLEK GEAVKLSGFG NFQIKKKKAR
     PGRNPRTGEI FLITARRVVT FKAGQKLKNK INNYLIKKNN NF