ID   IHFA_MYXXA              Reviewed;         129 AA.
AC   Q9K4Q3;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Integration host factor subunit alpha;
DE            Short=IHF-alpha;
GN   Name=ihfA; Synonyms=himA;
OS   Myxococcus xanthus.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=34;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DK1050;
RX   PubMed=11133949; DOI=10.1128/jb.183.2.557-569.2001;
RA   Moreno A.J., Fontes M., Murillo F.J.;
RT   "ihfA gene of the bacterium Myxococcus xanthus and its role in activation
RT   of carotenoid genes by blue light.";
RL   J. Bacteriol. 183:557-569(2001).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC       It is necessary for normal cell growth and the production of
CC       carotenoids in response to light.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AJ297483; CAC01236.1; -; Genomic_DNA.
DR   RefSeq; WP_002639669.1; NZ_JABFNT010000005.1.
DR   AlphaFoldDB; Q9K4Q3; -.
DR   SMR; Q9K4Q3; -.
DR   GeneID; 41360942; -.
DR   OMA; IYVRGFG; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..129
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000105011"
FT   REGION          87..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..114
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        115..129
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   129 AA;  14300 MW;  9AE2D1D64E05C0CE CRC64;
     MTKADIIEGV YEKVGFSKKE SAEIVELVFD TLKETLERGD KIKISGFGNF QVRQKKARVG
     RNPQTGKEIE ISARRVLTFR PSQVLKSALN GEAPPEDHAE IDAREEAAAD AAEARGEDFD
     EEGMEDMEG