ID   IHFA_NEIMA              Reviewed;         100 AA.
AC   P64392; A1IQY0; Q9JR90;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Integration host factor subunit alpha;
DE            Short=IHF-alpha;
GN   Name=ihfA; Synonyms=himA; OrderedLocusNames=NMA0938;
OS   Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 /
OS   Z2491).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122587;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15465 / Z2491;
RX   PubMed=10761919; DOI=10.1038/35006655;
RA   Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA   Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M.,
RA   Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G.,
RA   Barrell B.G.;
RT   "Complete DNA sequence of a serogroup A strain of Neisseria meningitidis
RT   Z2491.";
RL   Nature 404:502-506(2000).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AL157959; CAM08164.1; -; Genomic_DNA.
DR   RefSeq; WP_002214080.1; NC_003116.1.
DR   AlphaFoldDB; P64392; -.
DR   SMR; P64392; -.
DR   EnsemblBacteria; CAM08164; CAM08164; NMA0938.
DR   GeneID; 61280954; -.
DR   KEGG; nma:NMA0938; -.
DR   HOGENOM; CLU_105066_1_3_4; -.
DR   OMA; IYVRGFG; -.
DR   BioCyc; NMEN122587:NMA_RS04700-MON; -.
DR   Proteomes; UP000000626; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..100
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000105013"
FT   REGION          53..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   100 AA;  11422 MW;  4ADE0C995A1CF982 CRC64;
     MTLTKAELAD ILVDKVSNVT KNDAKEIVEL FFEEIRSTLA SGEEIKISGF GNFQLRDKPQ
     RPGRNPKTGE EVPITARRVV TFHASQKLKS MVEHYYDKQR