ID   IHFA_PSEPU              Reviewed;         100 AA.
AC   P0A127; Q52284;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Integration host factor subunit alpha;
DE            Short=IHF-alpha;
GN   Name=ihfA; Synonyms=himA;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8892836; DOI=10.1128/jb.178.21.6319-6326.1996;
RA   Calb R., Davidovitch A., Koby S., Giladi H., Goldenberg D., Margalit H.,
RA   Holtel A., Timmis K.N., Sanchez-Romero J.M., de Lorenzo V., Oppenheim A.B.;
RT   "Structure and function of the Pseudomonas putida integration host
RT   factor.";
RL   J. Bacteriol. 178:6319-6326(1996).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; U56904; AAB04060.1; -; Genomic_DNA.
DR   RefSeq; WP_003250679.1; NZ_WOWR01000033.1.
DR   AlphaFoldDB; P0A127; -.
DR   SMR; P0A127; -.
DR   STRING; 1240350.AMZE01000056_gene723; -.
DR   GeneID; 58530479; -.
DR   GeneID; 61891708; -.
DR   GeneID; 64091761; -.
DR   GeneID; 66676742; -.
DR   eggNOG; COG0776; Bacteria.
DR   OMA; IYVRGFG; -.
DR   OrthoDB; 1847472at2; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..100
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000105019"
FT   REGION          53..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   100 AA;  11500 MW;  6C3E655C1753A40E CRC64;
     MGALTKAEMA ERLYEELGLN KREAKELVEL FFEEIRHALE ENEQVKLSGF GNFDLRDKRQ
     RPGRNPKTGE EIPITARRVV TFRPGQKLKA RVEAYAGTKP